Updated on 2024/03/19

写真a

 
UENO SHINYA
 
Affiliation
Graduate School of Medicine F F

Degree

  • MD. PHD

Research Interests

  • Mechanism of Anesthetics

  • Neurophysiology

  • Neuroscience

  • GABA-A receptor

  • GABA-A receptor

  • ATP受容体

  • Exercise

  • neuropathic pain

Research Areas

  • Life Science / Neuroscience-general

  • Life Science / Anesthesiology

  • Life Science / Anesthesiology

  • Life Science / Neuroscience-general

  • Life Science / Neuroscience-general

  • Life Science / Physiology

  • Life Science / Physiology

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Professional Memberships

  • 東北てんかん談話会

  • 日本てんかん学会

  • 日本麻酔学会

  • 日本神経科学学会

  • 神経科学(Society for Neuroscience)

  • 日本生理学会

  • 日本薬理学会

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Papers

  • The role of neutrophil gelatinase-associated lipocalin and iron homeostasis in object recognition impairment in aged sepsis-survivor rats.

    Nikaido Y, Midorikawa Y, Furukawa T, Shimoyama S, Takekawa D, Kitayama M, Ueno S, Kushikata T, Hirota K

    Scientific reports   12 ( 1 )   249 - 249   2022.1

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  • Impaired Cognitive Function and Hippocampal Changes Following Chronic Diazepam Treatment in Middle-Aged Mice.

    Furukawa T, Nikaido Y, Shimoyama S, Masuyama N, Notoya A, Ueno S

    Frontiers in aging neuroscience   13   777404 - 777404   2021.11

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  • Benzodiazepine-induced cell growth inhibition via GABAA receptor- and TSPO- independent path

    Shimoyama S, Furukawa T, Ueno S.

    Hirosaki Medical Journal   2024.3

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  • Sex-related differences in the effect of exercise on protein profiles of serum in mice.

    Furukawa T, Shimoyama S, Kobayashi A, Tatara Y, Nikaido Y, Ueno S.

    Hirosaki Medical Journal   2024.3

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  • TRPA1 as a O2 sensor detects microenvironmental hypoxia in the mice anterior cingulate cortex.

    Ryo Kawabata, Shuji Shimoyama, Shinya Ueno, Ikuko Yao, Akiko Arata, Kohei Koga

    Scientific reports   13 ( 1 )   2960 - 2960   2023.2

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  • Intraperitoneal Administration of Etizolam Improves Locomotor Function in Mice After Spinal Cord Injury.

    Saruta K, Fukutoku T, Kumagai G, Nagaoki T, Tsukuda M, Nitobe Y, Wada K, Asari T, Fujita T, Sasaki I, Nikaido Y, Shimoyama S, Ueno S, Ishibashi Y

    Neurotrauma reports   4 ( 1 )   82 - 96   2023

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  • Copy number variations in Japanese children with autism spectrum disorder.

    Yui Sakamoto, Shuji Shimoyama, Tomonori Furukawa, Masaki Adachi, Michio Takahashi, Tamaki Mikami, Michito Kuribayashi, Ayako Osato, Daiki Tsushima, Manabu Saito, Shinya Ueno, Kazuhiko Nakamura

    Psychiatric genetics   31 ( 3 )   79 - 87   2021.2

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  • Sex-Related Differences in Anxiety and Functional Recovery after Spinal Cord Injury in Mice.

    Tatsuhiro Fukutoku, Gentaro Kumagai, Taku Fujita, Ayako Sasaki, Kanichiro Wada, Xizhe Liu, Toshihiro Tanaka, Hitoshi Kudo, Toru Asari, Yoshikazu Nikaido, Shinya Ueno, Yasuyuki Ishibashi

    Journal of neurotrauma   37 ( 21 )   2235 - 2243   2020.11

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  • GABA storage and release in the medial globus pallidus in L-DOPA-induced dyskinesia priming.

    Haruo Nishijima, Fumiaki Mori, Akira Arai, Gang Zhu, Koichi Wakabayashi, Motohiro Okada, Shinya Ueno, Noritaka Ichinohe, Chieko Suzuki, Tomoya Kon, Masahiko Tomiyama

    Neurobiology of disease   143   104979 - 104979   2020.9

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  • Anti-Epileptic Effects of FABP3 Ligand MF1 through the Benzodiazepine Recognition Site of the GABA(A) Receptor.

    Yabuki Y, Liu J, Kawahata I, Izumi H, Shinoda Y, Koga K, Ueno S, Shioda N, Fukunaga K

    International journal of molecular sciences   21 ( 15 )   2020.8

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  • Triphenyltin disrupts intracellular Zn<sup>2+</sup> homeostasis in rat thymic lymphocytes.

    Ueno T, Oyama K, Hyung YJ, Ueno S, Oyama Y

    Toxicology in vitro : an international journal published in association with BIBRA   65   104782   2020.6

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  • Triphenyltin disrupts intracellular Zn2+ homeostasis in rat thymic lymphocytes.

    Toshiya Ueno, Keisuke Oyama, Youn Jae Hyung, Shinya Ueno, Yasuo Oyama

    Toxicol in Vitro   65   104782 - 104782   2020.1

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  • Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.

    Shuji Shimoyama, Tomonori Furukawa, Yoshiki Ogata, Yoshikazu Nikaido, Kohei Koga, Yui Sakamoto, Shinya Ueno, Kazuhiko Nakamura

    PloS one   14 ( 9 )   e0222861 - e0222861   2019.9

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  • Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.

    Tomonori Furukawa, Yoshikazu Nikaido, Shuji Shimoyama, Yoshiki Ogata, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno

    Journal of anesthesia   33 ( 4 )   531 - 542   2019.8

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  • Phospholipase C-related inactive protein type-1 deficiency affects anesthetic electroencephalogram activity induced by propofol and etomidate in mice.

    Furukawa T, Nikaido Y, Shimoyama S, Ogata Y, Kushikata T, Hirota K, Kanematsu T, Hirata M, Ueno S

    Journal of anesthesia   33 ( 4 )   531 - 542   2019.8

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  • 〈一般演題抄録〉脊髄損傷モデルマウスにおける性差による損傷後不安障害および脊髄機能障害発現の違い

    福徳 達宏, 熊谷 玄太郎, 藤田 拓, 佐々木 綾子, 和田 簡一郎, 工藤 整, 浅利 亨, 二階堂 義和, 上野 伸哉, 石橋 恭之

    弘前医学   69 ( 1-4 )   201   2019.3

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  • 〈一般演題抄録〉遺伝子<i>Tspo</i> の発現制御メカニズムの解明

    下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉

    弘前医学   69 ( 1-4 )   207   2019.3

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  • 遺伝子Tspoの発現制御メカニズムの解明

    下山 修司, 古川 智範, 小潟 佳輝, 中村 和彦, 上野 伸哉

    弘前医学   69 ( 1-4 )   207 - 207   2019.3

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  • Lipopolysaccharide induces mouse translocator protein (18 kDa) expression via the AP-1 complex in the microglial cell line, BV-2.

    Shimoyama S, Furukawa T, Ogata Y, Nikaido Y, Koga K, Sakamoto Y, Ueno S, Nakamura K

    PloS one   14 ( 9 )   e0222861   2019

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  • Zonisamide Enhances Motor Effects of Levodopa, Not of Apomorphine, in a Rat Model of Parkinson's Disease.

    Haruo Nishijima, Yasuo Miki, Shinya Ueno, Masahiko Tomiyama

    Parkinson's disease   2018   8626783 - 8626783   2018.12

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  • Anti-hypersensitive effect of angiotensin (1-7) on streptozotocin-induced diabetic neuropathic pain in mice.

    Yoshiki Ogata, Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno, Koichi Tan-No

    European journal of pain (London, England)   23 ( 4 )   739 - 749   2018.12

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  • Anti‐hypersensitive effect of angiotensin (1‐7) on streptozotocin‐induced diabetic neuropathic pain in mice

    Yoshiki Ogata, Wataru Nemoto, Ryota Yamagata, Osamu Nakagawasai, Shuji Shimoyama, Tomonori Furukawa, Shinya Ueno, Koichi Tan‐No

    European Journal of Pain   23 ( 4 )   739 - 749   2018.12

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  • Chronic inflammatory pain induced GABAergic synaptic plasticity in the adult mouse anterior cingulate cortex.

    Kohei Koga, Shuji Shimoyama, Akihiro Yamada, Tomonori Furukawa, Yoshikazu Nikaido, Hidemasa Furue, Kazuhiko Nakamura, Shinya Ueno

    Molecular pain   14   1744806918783478 - 1744806918783478   2018.6

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  • Poor motor-function recovery after spinal-cord injury in anxiety-model mice with phospholipase C-related catalytically inactive protein type 1 knockout.

    Taku Fujita, Gentaro Kumagai, Xizhe Liu, Kanichiro Wada, Toshihiro Tanaka, Hitoshi Kudo, Toru Asari, Tatsuhiro Fukutoku, Ayako Sasaki, Yohshiro Nitobe, Yoshikazu Nikaido, Ken-Ichi Furukawa, Masato Hirata, Takashi Kanematsu, Shinya Ueno, Yasuyuki Ishibashi

    Journal of neurotrauma   35 ( 12 )   1379 - 1386   2018.1

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  • Levodopa treatment and dendritic spine pathology.

    Haruo Nishijima, Tatsuya Ueno, Yukihisa Funamizu, Shinya Ueno, Masahiko Tomiyama

    Movement disorders : official journal of the Movement Disorder Society   33 ( 6 )   877 - 888   2017.9

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  • Morphological dendritic spine changes of medium spiny neurons in the nucleus accumbens in 6-hydroxydopamine-lesioned rats treated with levodopa.

    Yukihisa Funamizu, Haruo Nishijima, Tatsuya Ueno, Shinya Ueno, Hiroki Mizukami, Soroku Yagihashi, Masahiko Tomiyama

    Neuroscience research   121   49 - 53   2017.8

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  • Propofol Anesthesia Is Reduced in Phospholipase C-Related Inactive Protein Type-1 Knockout Mice.

    Yoshikazu Nikaido, Tomonori Furukawa, Shuji Shimoyama, Junko Yamada, Keisuke Migita, Kohei Koga, Tetsuya Kushikata, Kazuyoshi Hirota, Takashi Kanematsu, Masato Hirata, Shinya Ueno

    The Journal of pharmacology and experimental therapeutics   361 ( 3 )   367 - 374   2017.6

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  • Spine enlargement of pyramidal tract-type neurons in the motor cortex of a rat model of levodopa-induced dyskinesia

    Tatsuya Ueno, Haruo Nishijima,Shinya Ueno and Masahiko Tomiyama

    Frontiers in Neuroscience   11   205   2017.3

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  • Activations of muscarinic M1 receptors in the anterior cingulate cortex contribute to the antinociceptive effect via GABAergic transmission

    Kohei Koga, Yu Matsuzaki, Kenji Honda, Fumihiro Eto, Tomonori Furukawa, Keisuke Migita, Keiichi Irie, Kenichi Mishima, and Shinya Ueno

    Molecular Pain   13   174480691769233   2017.2

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  • Chronic diazepam administration increases the expression of Lcn2 in the CNS.

    Tomonori Furukawa, Shuji Shimoyama, Yasuo Miki, Yoshikazu Nikaido, Kohei Koga, Kazuhiko Nakamura, Koichi Wakabayashi, Shinya Ueno

    Pharmacology research & perspectives   5 ( 1 )   e00283 - e00283   2017.2

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  • 〈一般演題抄録〉ジアゼパム長期投与マウス脳組織のトランスクリプトーム解析

    古川 智範, 下山 修司, 二階堂 義和, 古賀 浩平, 中村 和彦, 上野 伸哉

    弘前医学   67 ( 2-4 )   186   2017

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  • 〈一般演題抄録〉ジアゼパム長期投与マウスにおける脳内 Lcn2 発現および認知機能の解析

    古川 智範, 二階堂 義和, 下山 修司, 三木 康生, 古賀 浩平, 中村 和彦, 若林 孝一, 上野 伸哉

    弘前医学   68 ( 1 )   88   2017

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  • 〈一般演題抄録〉うつ病モデルラットは内側前頭前野機能異常を起こす

    二階堂 義和, 古川 智範, 下山 修司, 古賀 浩平, 上野 伸哉

    弘前医学   67 ( 2-4 )   185   2017

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  • Levodopa-induced morphologic changes of prefrontal pyramidal tract-type neurons in a rat model of Parkinson's disease

    Haruo Nishijima, Tatsuya Ueno, Shinya Ueno, Fumiaki Mori, Yasuo Miki, Masahiko Tomiyama

    NEUROSCIENCE RESEARCH   115   54 - 58   2016.10

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  • HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus

    Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M. Egan, Shinya Ueno

    MOLECULAR PHARMACOLOGY   90 ( 2 )   116 - 126   2016.8

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  • Duloxetine increases the effects of levodopa in a rat model of Parkinson's disease

    Haruo Nishijima, Tatsuya Ueno, Shinya Ueno, Masahiko Tomiyama

    Neurology and Clinical Neuroscience   4 ( 4 )   129 - 133   2016.3

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  • cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats.

    Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Ueno

    Behavioural brain research   297   251 - 258   2016.1

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  • cis-3-Hexenol and trans-2-hexenal mixture prevents development of PTSD-like phenotype in rats

    Yoshikazu Nikaido, Junko Yamada, Keisuke Migita, Yuko Shiba, Tomonori Furukawa, Toshihiro Nakashima, Shinya Ueno

    BEHAVIOURAL BRAIN RESEARCH   297   251 - 258   2016.1

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  • GABA<sub>A</sub> 受容体応答の制御機構

    上野 伸哉, 古川 智範, 二階堂 義和, 下山 修司, 柴 祐子, 山田 順子

    弘前医学   66 ( 2-4 )   105 - 109   2016

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  • Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the β2-subunit of the nicotinic acetylcholine receptor.

    Yuko Shiba, Fumiaki Mori, Junko Yamada, Keisuke Migita, Yoshikazu Nikaido, Koichi Wakabayashi, Sunao Kaneko, Motohiro Okada, Shinichi Hirose, Shinya Ueno

    Neuroscience research   100   46 - 54   2015.11

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  • Spontaneous epileptic seizures in transgenic rats harboring a human ADNFLE missense mutation in the beta 2-subunit of the nicotinic acetylcholine receptor

    Yuko Shiba, Fumiaki Mori, Junko Yamada, Keisuke Migita, Yoshikazu Nikaido, Koichi Wakabayashi, Sunao Kaneko, Motohiro Okada, Shinichi Hirose, Shinya Ueno

    NEUROSCIENCE RESEARCH   100   46 - 54   2015.11

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  • p62 Deficiency Enhances alpha-Synuclein Pathology in Mice

    Kunikazu Tanji, Saori Odagiri, Yasuo Miki, Atsushi Maruyama, Yoshikazu Nikaido, Junsei Mimura, Fumiaki Mori, Eiji Warabi, Toru Yanagawa, Shinya Ueno, Ken Itoh, Koichi Wakabayashi

    BRAIN PATHOLOGY   25 ( 5 )   552 - 564   2014.10

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  • Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motor cortex of a rat model of levodopa-induced dyskinesia.

    Tatsuya Ueno, Junko Yamada, Haruo Nishijima, Akira Arai, Keisuke Migita, Masayuki Baba, Shinya Ueno, Masahiko Tomiyama

    Neurobiology of disease   64   142 - 149   2014.4

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  • Morphological and electrophysiological changes in intratelencephalic-type pyramidal neurons in the motor cortex of a rat model of levodopa-induced dyskinesia

    Tatsuya Ueno, Junko Yamada, Haruo Nishijima, Akira Arai, Keisuke Migita, Masayuki Baba, Shinya Ueno, Masahiko Tomiyama

    NEUROBIOLOGY OF DISEASE   64   142 - 149   2014.4

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  • Morphologic changes of dendritic spines of striatal neurons in the levodopa-induced dyskinesia model.

    Haruo Nishijima, Satoko Suzuki, Tomoya Kon, Yukihisa Funamizu, Tatsuya Ueno, Rie Haga, Chihiro Suzuki, Akira Arai, Tamaki Kimura, Chieko Suzuki, Reiko Meguro, Yasuo Miki, Junko Yamada, Keisuke Migita, Noritaka Ichinohe, Shinya Ueno, Masayuki Baba, Masahiko Tomiyama

    Movement disorders : official journal of the Movement Disorder Society   29 ( 3 )   336 - 343   2014.3

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  • Association of nonsense mutation in GABRG2 with abnormal trafficking of GABA(A) receptors in severe epilepsy

    Atsushi Ishii, Takeshi Kanaumi, Miwa Sohda, Yoshio Misumi, Bo Zhang, Naoto Kakinuma, Yoshiko Haga, Kazuyoshi Watanabe, Sen Takeda, Motohiro Okada, Shinya Ueno, Sunao Kaneko, Sachio Takashima, Shinichi Hirose

    EPILEPSY RESEARCH   108 ( 3 )   420 - 432   2014.3

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  • Morphologic Changes of Dendritic Spines of Striatal Neurons in the Levodopa-Induced Dyskinesia Model

    Haruo Nishijima, Satoko Suzuki, Tomoya Kon, Yukihisa Funamizu, Tatsuya Ueno, Rie Haga, Chihiro Suzuki, Akira Arai, Tamaki Kimura, Chieko Suzuki, Reiko Meguro, Yasuo Miki, Junko Yamada, Keisuke Migita, Noritaka Ichinohe, Shinya Ueno, Masayuki Baba, Masahiko Tomiyama

    MOVEMENT DISORDERS   29 ( 3 )   336 - 343   2014.2

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  • The kick-in system: a novel rapid knock-in strategy.

    Yuko Tomonoh, Masanobu Deshimaru, Kimi Araki, Yasuhiro Miyazaki, Tomoko Arasaki, Yasuyoshi Tanaka, Haruna Kitamura, Fumiaki Mori, Koichi Wakabayashi, Sayaka Yamashita, Ryo Saito, Masayuki Itoh, Taku Uchida, Junko Yamada, Keisuke Migita, Shinya Ueno, Hiroki Kitaura, Akiyoshi Kakita, Christoph Lossin, Yukio Takano, Shinichi Hirose

    PloS one   9 ( 2 )   e88549 - e88549   2014.2

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  • The Kick-In System: A Novel Rapid Knock-In Strategy

    Yuko Tomonoh, Masanobu Deshimaru, Kimi Araki, Yasuhiro Miyazaki, Tomoko Arasaki, Yasuyoshi Tanaka, Haruna Kitamura, Fumiaki Mori, Koichi Wakabayashi, Sayaka Yamashita, Ryo Saito, Masayuki Itoh, Taku Uchida, Junko Yamada, Keisuke Migita, Shinya Ueno, Hiroki Kitaura, Akiyoshi Kakita, Christoph Lossin, Yukio Takano, Shinichi Hirose

    PLOS ONE   9 ( 2 )   e88549   2014.2

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  • A novel prophylactic effect of furosemide treatment on autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE).

    Junko Yamada, Gang Zhu, Motohiro Okada, Shinichi Hirose, Shukuko Yoshida, Yuko Shiba, Keisuke Migita, Fumiaki Mori, Takayuki Sugawara, Lei Chen, Fang Liu, Shuichi Yoshida, Shinya Ueno, Sunao Kaneko

    Epilepsy research   107 ( 1-2 )   127 - 137   2013.11

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  • A novel prophylactic effect of furosemide treatment on autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE)

    Junko Yannada, Gang Zhu, Motohiro Okada, Shinichi Hirose, Shukuko Yoshida, Yuko Shiba, Keisuke Migita, Fumiaki Mori, Takayuki Sugawara, Lei Chen, Fang Liu, Shuichi Yoshida, Shinya Ueno, Sunao Kaneko

    EPILEPSY RESEARCH   107 ( 1-2 )   127 - 137   2013.11

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  • 増大特集 細胞表面受容体 構造的特徴:1回膜貫通型◆受容体の遺伝子: GABAA受容体γ-subunitを介した機能変異

    上野 伸哉

    生体の科学   64 ( 5 )   482 - 483   2013.10

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  • Drebrin immunoreactivity in the striatum of a rat model of levodopa-induced dyskinesia.

    Haruo Nishijima, Akira Arai, Tamaki Kimura, Fumiaki Mori, Junko Yamada, Keisuke Migita, Koichi Wakabayashi, Masayuki Baba, Shinya Ueno, Masahiko Tomiyama

    Neuropathology : official journal of the Japanese Society of Neuropathology   33 ( 4 )   391 - 396   2013.8

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  • Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice.

    Tomoya Kitayama, Katsuya Morita, Rizia Sultana, Nami Kikushige, Keisuke Mgita, Shinya Ueno, Masato Hirata, Takashi Kanematsu

    Molecular pain   9   23 - 23   2013.3

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  • Phospholipase C-related but catalytically inactive protein modulates pain behavior in a neuropathic pain model in mice

    Tomoya Kitayama, Katsuya Morita, Rizia Sultana, Nami Kikushige, Keisuke Mgita, Shinya Ueno, Masato Hirata, Takashi Kanematsu

    Molecular Pain   9 ( 1 )   23   2013.1

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  • Properties of a novel GABAA receptor γ2 subunit mutation associated with seizures.

    Keisuke Migita, Junko Yamada, Yoshikazu Nikaido, XiuYu Shi, Sunao Kaneko, Shinichi Hirose, Shinya Ueno

    Journal of pharmacological sciences   121 ( 1 )   84 - 87   2013.1

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  • Properties of a Novel GABA<sub>A</sub> Receptor γ<sub>2</sub> Subunit Mutation Associated With Seizures

    Migita Keisuke, Yamada Junko, Nikaido Yoshikazu, Shi XiuYu, Kaneko Sunao, Hirose Shinichi, Ueno Shinya

    Journal of Pharmacological Sciences   121 ( 1 )   84 - 87   2013

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  • Identification of the angiotensin converting enzyme inhibitors in the local product of Aomori prefecture

    Itagaki Shirou, Uchiyama Michiko, Kanazawa Sachiko, Hosoi Kazuhiro, Terui Kazufumi, Shimoyama Ritsuko, Tsuchida Shigeki, Ueno Shinya, Hayakari Makoto

    Hirosaki Medical Journal   64 ( 1 )   50 - 57   2013

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  • Drebrin immunoreactivity in the striatum of a rat model of levodopa-induced dyskinesia

    Haruo Nishijima, Akira Arai, Tamaki Kimura, Fumiaki Mori, Junko Yamada, Keisuke Migita, Koichi Wakabayashi, Masayuki Baba, Shinya Ueno, Masahiko Tomiyama

    NEUROPATHOLOGY   33 ( 4 )   391 - 396   2012.12

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  • Dysfunction of extrasynaptic GABAergic transmission in phospholipase C-related, but catalytically inactive protein 1 knockout mice is associated with an epilepsy phenotype

    Zhu, G. et al.

    J Pharmacol Exp Ther   340 ( 3 )   520 - 528   2012.3

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  • Dysfunction of Extrasynaptic GABAergic Transmission in Phospholipase C-Related, but Catalytically Inactive Protein 1 Knockout Mice Is Associated with an Epilepsy Phenotype

    Gang Zhu, Shukuko Yoshida, Keisuke Migita, Junko Yamada, Fumiaki Mori, Masahiko Tomiyama, Koichi Wakabayashi, Takashi Kanematsu, Masato Hirata, Sunao Kaneko, Shinya Ueno, Motohiro Okada

    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS   340 ( 3 )   520 - 528   2012.3

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  • Phenotypes of pain behavior in phospholipase C-related but catalytically inactive protein type 1 knockout mice

    Migita, K., Tomiyama, M., Yamada, J., Fukuzawa, M., Kanematsu, T., Hirata, M., Ueno, S.

    Molecular Pain   7   79   2011.10

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  • Phenotypes of pain behavior in phospholipase C-related but catalytically inactive protein type 1 knockout mice

    Keisuke Migita, Masahiko Tomiyama, Junko Yamada, Masashi Fukuzawa, Takashi Kanematsu, Masato Hirata, Shinya Ueno

    MOLECULAR PAIN   7   79   2011.1

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  • 痛み

    右田 啓介, 山田 順子, 上野 伸哉

    月刊臨床神経科学(中外医学社)   29   836 - 838   2011

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  • Involvement of P2X2 and P2X3 receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy.

    Migita K, Honda K, Yamada J, Takano Y, Ueno S.

    Hirosaki Med J   Supple1 ( 61 )   255 - 261   2010.7

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  • Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy

    Migita, K., Moriyama, T., Koguchi, M., Honda, K., Katsuragi, T., Takano, Y., Ueno, S.

    Neuroci Lett   452 ( 2 )   200 - 203   2009.3

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  • Modulation of P2X receptors in dorsal root ganglion neurons of streptozotocin-induced diabetic neuropathy

    Keisuke Migita, Tomoko Moriyama, Masako Koguchi, Kenji Honda, Takeshi Katsuragi, Yukio Takano, Shinya Ueno

    NEUROSCIENCE LETTERS   452 ( 2 )   200 - 203   2009.3

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  • Orexin A decreases ketamine-induced anesthesia time in the rat: the relevance to brain noradrenergic neuronal activity.

    Tose R, Kushikata T, Yoshida H, Kudo M, Furukawa K, Ueno S, Hirota K.

    Anesth Analg   108 ( 2 )   491 - 495   2009.2

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  • Orexin A Decreases Ketamine-Induced Anesthesia Time in the Rat: The Relevance to Brain Noradrenergic Neuronal Activity

    Ryuji Tose, Tetsuya Kushikata, Hitoshi Yoshida, Mihoko Kudo, Kenichi Furukawa, Shinya Ueno, Kazuyoshi Hirota

    ANESTHESIA AND ANALGESIA   108 ( 2 )   491 - 495   2009.2

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  • Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat

    Brain Res   2009.1

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  • Interaction between orexinergic neurons and NMDA receptors in the control of locus coeruleus-cerebrocortical noradrenergic activity of the rat

    Ryuji Tose, Tetsuya Kushikata, Hitoshi Yoshida, Mihoko Kudo, Kenichi Furukawa, Shinya Ueno, Kazuyoshi Hirota

    BRAIN RESEARCH   1250   81 - 87   2009.1

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  • Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype

    Zhu, G. et al.

    J Neurosci   28 ( 47 )   12465 - 12476   2008.11

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  • Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype

    Gang Zhu, Motohiro Okada, Shukuko Yoshida, Shinya Ueno, Fumiaki Mori, Tomoko Takahara, Ryo Saito, Yoshiki Miura, Akihiro Kishi, Masahiko Tomiyama, Akira Sato, Toshio Kojima, Goryu Fukuma, Koichi Wakabayashi, Koji Hase, Hiroshi Ohno, Hiroshi Kijima, Yukio Takano, Akihisa Mitsudome, Sunao Kaneko, Shinichi Hirose

    JOURNAL OF NEUROSCIENCE   28 ( 47 )   12465 - 12476   2008.11

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  • Caffeine-inducible ATP release is mediated by Ca2+-signal transducing system from the endoplasmic reticulum to mitochondria

    Naunyn Schmiedebergs Arch Pharmacol   378 ( 1 )   93 - 101   2008.7

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  • Caffeine-inducible ATP release is mediated by Ca2+-signal transducing system from the endoplasmic reticulum to mitochondria.

    Katsuragi T, Sato C, Usune S, Ueno S, Segawa M, Migita K

    Naunyn-Schmiedeberg's archives of pharmacology   378 ( 1 )   93 - 101   2008.7

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  • A study of the perception of burden in the Japanese family with the Alzheimer's disease: perception of burden in nursing the Alzheimer patient: focused on the connection with burnout scale and coping strategies

    Japanese journal of geriatric psychiatry   19 ( 3 )   333 - 341   2008.3

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  • Molecular Basis for the GABAA Receptor-Mediated Tonic Inhibition in Rat Somatosensory Cortex. "jointly worked"

    Yamada J, Furukawa T, Ueno S, Yamamoto S, Fukuda A.

    Cereb Cortex   17 ( 8 )   1782 - 1787   2007.8

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  • Insertion of {alpha}7 Nicotinic Receptors at Neocortical Layer V GABAergic Synapses Is Induced by a Benzodiazepine, Midazolam. "jointly worked"

    Yamamoto S, Yamada J, Ueno S, Kubota H, Furukawa T, Yamamoto S, Fukuda A.

    Cereb Cortex   17 ( 3 )   653 - 660   2007.8

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  • Molecular basis for the GABA(A) receptor-mediated tonic inhibition in rat somatosensory cortex

    Junko Yamada, Tomonori Furukawa, Shinya Ueno, Sumii Yamamoto, Atsuo Fukuda

    CEREBRAL CORTEX   17 ( 8 )   1782 - 1787   2007.8

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  • Insertion of alpha 7 nicotinic receptors at neocortical layer V GABAergic synapses is induced by a benzodiazepine, midazolam

    Sumii Yamamoto, Junko Yamada, Shinya Ueno, Hisahiko Kubota, Tomonori Furukawa, Seiji Yamamoto, Atsuo Fukuda

    CEREBRAL CORTEX   17 ( 3 )   653 - 660   2007.3

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  • Chrna 4に異常を持つ遺伝子改変モデル動物の神経科学的解析.

    岡田 元宏, 朱 剛, 上野 伸哉, 兼子 直

    厚生労働省精神・神経疾患研究委託費(16指-3)研究報告書   81 - 86   2007

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  • Effects of interleukin-1 beta on hippocampal glutamate and GABA releases associated with Ca2+-induced Ca2+ releasing systems

    Gang Zhu, Motohiro Okada, Shukuko Yoshida, Furniaki Mori, Shinya Ueno, Koichi Wakabayashi, Sunao Kaneko

    EPILEPSY RESEARCH   71 ( 2-3 )   107 - 116   2006.10

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  • Effects of interleukin-1beta on hippocampal glutamate and GABA releases associated with Ca(2+)-induced Ca(2+) releasing systems. "jointly worked"

    Zhu G, Okada M, Yoshida S, Mori F, Ueno S, Wakabayashi K, Kaneko S.

    Epilepsy Res   71 ( 2-3 )   107 - 116   2006.7

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  • Propofol, an anesthetic possessing neuroprotective action against oxidative stress, promotes the process of cell death induced by H2O2 in rat thymocytes. "jointly worked"

    Chikutei K, Oyama TM, Ishida S, Okano Y, Kobayashi M, Matsui H, Horimoto K, Nishimura Y, Ueno SY, Oyama Y.

    Eur J Pharmacol   540 ( 1-3 )   18 - 23   2006.7

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  • ヒトてんかんと同じ遺伝子異常をもつモデル動物

    廣瀬伸一 他

    脳と精神の医学   17 ( 2 )   157 - 160   2006.2

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  • Cytometric analysis of lidocaine-induced cytotoxicity: a model experiment using rat thymocytes. "joinetly worked"

    Nishimura Y, Kanada A, Yamaguchi JY, Horimoto K, Kobayashi M, Tatsuishi T, Kanemaru K, Ueno SY, Oyama Y.

    Toxicology   218 ( 1 )   48 - 57   2006.1

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  • Brain-type creatine kinase activates neuron-specific K+-Cl- co-transporter KCC2. "jointely worked"

    Inoue K, Yamada J, Ueno S, Fukuda A.

    J Neurochem   96 ( 2 )   598 - 608   2006.1

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  • Brain-type creatine kinase activates neuron-specific K(+)-Cl(-) co-transporter KCC2

    K Inoue, J Yamada, S Ueno, A Fukuda

    JOURNAL OF NEUROCHEMISTRY   96 ( 2 )   598 - 608   2006.1

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  • ヒトてんかんと同じ遺伝子異常をもつモデル動物

    岡田 元宏, 朱 剛, 上野 伸哉

    脳と精神の医学 17   157 - 160   2006

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  • ヒトてんかんと同じ遺伝子異常をもつ組換え動物の作出

    岡田 元宏, 朱 剛, 上野 伸哉

    精神薬療研究年報 38   191 - 196   2006

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  • Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex

    CW Huang, S Ueno, M Okada, S Kaneko

    EPILEPSY RESEARCH   67 ( 1-2 )   51 - 60   2005.10

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  • Characterization of newly cloned variant of rat glycine receptor alpha1 subunit. "jointly worked"

    Inoue K, Ueno S, Yamada J, Fukuda A.

    Biochem Biophys Res Commun   327 ( 1 )   300 - 305   2005.2

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  • Characterization of newly cloned variant of rat glycine receptor alpha 1 subunit

    K Inoue, S Ueno, J Yamada, A Fukuda

    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS   327 ( 1 )   300 - 305   2005.2

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  • Differential functional expression of cation-Cl- cotransporter mRNAs (KCC1, KCC2, and NKCC1) in rat trigeminal nervous system. "jointly worked"

    Toyoda H, Yamada J, Ueno S, Okabe A, Kato H, Sato K, Hashimoto K, Fukuda A.

    Brain Res Mol Brain Res   133 ( 1 )   12 - 18   2005.1

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  • Transgenic expression of enhanced green fluorescent protein enables direct visualization for physiological studies of vasopressin neurons and isolated nerve terminals of the rat. "jointly worked"

    Ueta Y, Fujihara H, Serino R, Dayanithi G, Ozawa H, Matsuda K, Kawata M, Yamada J, Ueno S, Fukuda A, Murphy D.

    Endocrinology   146 ( 1 )   406 - 413   2005.1

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  • Differential functional expression of cation-Cl(-) cotransporter mRNAs (KCC1, KCC2, and NKCC1) in rat trigeminal nervous system

    H Toyoda, J Yamada, S Ueno, A Okabe, H Kato, K Sato, K Hashimoto, A Fukuda

    MOLECULAR BRAIN RESEARCH   133 ( 1 )   12 - 18   2005.1

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  • Transgenic expression of enhanced green fluorescent protein enables direct visualization for physiological studies of vasopressin neurons and isolated nerve terminals of the rat

    Y Ueta, H Fujihara, R Serino, G Dayanithi, H Ozawa, K Matsuda, M Kawata, J Yamada, S Ueno, A Fukuda, D Murphy

    ENDOCRINOLOGY   146 ( 1 )   406 - 413   2005.1

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  • Insertion of alpha 7 nicotinic receptors at neocortical layer V GABAergic synapses is induced by a benzodiazepine, via PKC pathway

    Yamamoto Sumii, Yamada Jyunko, Ueno Shinya, Kubota Hisahiko, Yamamoto Seiji, Fukuda Atsuo

    Proceedings of Annual Meeting of the Physiological Society of Japan   2005 ( 0 )   S142 - S142   2005

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    CiNii Research

  • ヒトてんかんと同じ遺伝子異常をもつ組換え動物の作出

    岡田 元宏, 上野 伸哉, 廣瀬 伸一, 兼子 直

    精神薬療研究年報 37   160 - 164   2005

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    CiNii Research

  • Malfunction of respiratory-related neuronal activity in Na+, K+-ATPase alpha2 subunit-deficient mice is attributable to abnormal Cl- homeostasis in brainstem neurons. "jointly worked"

    Ikeda K, Onimaru H, Yamada J, Inoue K, Ueno S, Onaka T, Toyoda H, Arata A, Ishikawa TO, Taketo MM, Fukuda A, Kawakami K.

    J Neurosci   24 ( 47 )   10693 - 10701   2004.11

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  • Malfunction of respiratory-related neuronal activity in Na(+), K(+)-ATPase alpha 2 subunit-deficient mice is attributable to abnormal Cl(-) homeostasis in brainstem neurons

    K Ikeda, H Onimaru, J Yamada, K Inoue, S Ueno, T Onaka, H Toyoda, A Arata, T Ishikawa, MM Taketo, A Fukuda, K Kawakami

    JOURNAL OF NEUROSCIENCE   24 ( 47 )   10693 - 10701   2004.11

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  • Zonisamide at clinically relevant concentrations inhibits field EPSP but not presynaptic fiber volley in rat frontal cortex. "jointly worked"

    Huang CW, Ueno S, Okada M, Kaneko S.

    Epilepsy Res   67 ( 1-2 )   51 - 60   2004.10

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  • Interaction of neuron-specific K+-Cl- cotransporter, KCC2, with brain-type creatine kinase. "jointly worked"

    Inoue K, Ueno S, Fukuda A.

    FEBS Lett   564 ( 1-2 )   131 - 135   2004.4

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  • Interaction of neuron-specific K(+)-Cl(-) cotransporter, KCC2, with brain-type creatine kinase

    K Inoue, S Ueno, A Fukuda

    FEBS LETTERS   564 ( 1-2 )   131 - 135   2004.4

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  • Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in mice. "jointly worked"

    Sakurada T, Matsumura T, Moriyama T, Sakurada C, Ueno S, Sakurada S.

    Pharmacol Biochem Behav   75 ( 1 )   115 - 121   2003.4

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  • Differential effects of intraplantar capsazepine and ruthenium red on capsaicin-induced desensitization in mice.

    Sakurada T, Matsumura T, Moriyama T, Sakurada C, Ueno S, Sakurada S

    Pharmacology, biochemistry, and behavior   75 ( 1 )   115 - 21   2003.4

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  • Measurement of dorsal root ganglion P2X mRNA by SYBR Green fluorescence

    S Ueno, H Yamada, T Moriyama, K Honda, Y Takano, H Kamiya, T Katsuragi

    BRAIN RESEARCH PROTOCOLS   10 ( 2 )   95 - 101   2002.10

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  • Downregulation of P2X(3) receptor-dependent sensory functions in A/J inbred mouse strain

    M Tsuda, Y Shigemoto-Mogami, S Ueno, S Koizumi, H Ueda, T Iwanaga, K Inoue

    EUROPEAN JOURNAL OF NEUROSCIENCE   15 ( 9 )   1444 - 1450   2002.5

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Books

  • W.F.Boron/E.L.Boulpaep MEDICAL PHYSIOLOGY A Cellular and Molecular Approach Updated edition

    ( Role: Joint translator)

    2011.9 

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Review Papers

  • 抗不安薬ジアゼパムの長期使用による海馬神経機能への影響

    古川智範, 二階堂義和, 二階堂義和, 下山修司, 下山修司, 上野伸哉, 上野伸哉

    日本脳科学会プログラム・講演抄録集   47th   2020

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    J-GLOBAL

  • GABAA受容体応答の制御機構

    上野伸哉, 古川智範, 二階堂義和, 下山修司, 柴祐子, 山田順子,

    弘前医学   2016

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  • GABAA受容体g-subunitを介した機能変異

    上野伸哉

    生体の科学   2013.11

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  • 可塑性と臨床:痛み

    右田啓介, 山田順子, 上野伸哉

    Clinical Neurosci   29 ( 7 )   836 - 838   2011.7

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  • Generation of epileptic animal model brearing a genetic abnormality identified in autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) of human

    20   39 - 44   2009.10

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  • 医学部医学科3年生に対するチュートリアル導入授業-「ラージクラス・チュートリアル」による試み-

    加藤博之 他

    21世紀教育フォーラム   4   17 - 26   2009.3

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  • Rats Harboring S284L Chrna4 Mutation Show Attenuation of Synaptic and Extrasynaptic GABAergic Transmission and Exhibit the Nocturnal Frontal Lobe Epilepsy Phenotype

    Gang Zhu, Motohiro Okada, Shukuko Yoshida, Shinya Ueno, Fumiaki Mori, Tomoko Takahara, Ryo Saito, Yoshiki Miura, Akihiro Kishi, Masahiko Tomiyama, Akira Sato, Toshio Kojima, Goryu Fukuma, Koichi Wakabayashi, Koji Hase, Hiroshi Ohno, Hiroshi Kijima, Yukio Takano, Akihisa Mitsudome, Sunao Kaneko, Shinichi Hirose

    JOURNAL OF NEUROSCIENCE   28 ( 47 )   12465 - 12476   2008.11

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    Web of Science

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Social Activities

  • 放送大学講師

    2007.06