Updated on 2021/12/08

写真a

 
KASHIWAGI AKIKO
 
Affiliation
Division of Natural Sciences Agriculture and Life Science Section
Full-time staff
Faculty of Agriculture and Life Science Department of Applied Biosciences

Degree

  • 博士(工学)

Research Areas

  • Life Science / Evolutionary biology

Professional Memberships

  • バイオインダストリー協会

  • 日本生物工学会

  • 日本進化学会

  • 日本生物物理学会

Papers

  • The single-stranded RNA bacteriophage Qβ adapts rapidly to high temperatures: an evolution experiment

    Md. Tanvir Hossain, Toma Yokono and Akiko Kashiwagi

    Viruses-Basel   12 ( 6 )   638   2020.6

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Complete genomic sequence of the Pseudomonas lactis bacteriophage HU1 isolated from raw cow’s milk

    Chikage Tanaka, Takahiro Nakayama, Takahiro Toba, and Akiko Kashiwagi

    Archives of Virology   165 ( 1 )   215 - 217   2020.1

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    Language:English   Publishing type:Research paper (scientific journal)   Kind of work:Joint Work  

  • Influence of adaptive mutations, from thermal adaptation experiments, on the infection cycle of RNA bacteriophage Qβ.

    Akiko Kashiwagi, Tamami Kadoya, Naoya Kumasaka, Tomofumi Kumagai, Fumie Sano Tsushima, Tetsuya Yomo

    Archives of virology   163 ( 10 )   2655 - 2662   2018.10

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  • A Lytic Bacteriophage for Controlling Pseudomonas lactis in Raw Cow's Milk.

    Chikage Tanaka, Kohsuke Yamada, Honami Takeuchi, Yoshio Inokuchi, Akiko Kashiwagi, Takahiro Toba

    Applied and environmental microbiology   84 ( 18 )   2018.9

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  • Characterization of a single mutation in TraQ in a strain of Escherichia coli partially resistant to Qβ infection

    Akiko Kashiwagi, Hikari Kitamura, Fumie Sano Tsushima

    Frontiers in Microbiology   6   124   2015.2

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  • Contribution of silent mutations to thermal adaptation of RNA bacteriophage Qβ

    Kashiwagi A, Sugawara R, Sano Tsushima F, Kumagai T, Yomo T.

    Journal of Virology   88 ( 19 )   11459 - 11468   2014.10

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  • Adaptation of a cyanobacterium to a biochemically rich environment in experimental evolution as an initial step toward a chloroplast-like state

    Hosoda K, Habuchi M, Suzuki S, Miyazaki M, Takikawa G, Sakurai T, Kashiwagi A, Sueyoshi M, Matsumoto Y, Kiuchi A, Mori K, Yomo T.

    PLoS ONE   9 ( 5 )   e98337   2014.5

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  • Quantitative comparison of the RNA bacteriophage Qβ life cycle in rich and minimal media

    Tomonori Inomata, Hitomi Kimura, Haruki Hayasaka, Akinori Shiozaki, Yasuhiro Fujita, Akiko Kashiwagi

    Archives of Virology   2012.7

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  • Ongoing phenotypic and genomic changes in experimental coevolution of RNA bacteriophage Qβ and Escherichia coli

    Akiko Kashiwagi, Tetsuya Yomo

    PLoS Genetics   7 ( 8 )   2011.8

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  • Adaptation by stochastic switching of a monostable genetic circuit in Escherichia coli

    Saburo Tsuru, Nao Yasuda, Yoshie Murakami, Junya Ushioda, Kotaro Mori, Akiko Kashiwagi, Shingo Suzuki, Bei-Wen Ying, Tetsuya Yomo

    Molecular Systems Biology   7   2011.3

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  • Cooperative adaptation to establishment of a synthetic bacterial mutualism

    Kazufumi Hosoda, Shingo Suzuki, Yoshinori Yamauchi, Yasunori Shiroguchi, Akiko Kashiwagi, Naoaki Ono, Kotaro Mori, Tetsuya Yomo

    PLoS ONE   6 ( 2 )   2011.2

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  • Transition from positive to neutral in mutation fixation along with continuing rising fitness in thermal adaptive evolution

    Toshihiko Kishimoto, Leo Iijima, Makoto Tatsumi, Naoaki Ono, Ayana Oyake, Tomomi Hashimoto, Moe Matsuo, Masato Okubo, Shingo Suzuki, Kotaro Mori, Akiko Kashiwagi, Chikara Furusawa, Bei-Wen Ying, Tetsuya Yomo

    PLoS Genetics   6 ( 10 )   2010.10

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  • Noisy growth rate leads to fluctuating protein concentration in bacteria

    Saburo Tsuru, Junya Ichinose, Akiko Kashiwagi, Bei-Wen Ying, Kunihiko Kaneko, Tetsuya Yomo

    Physical Biology   6   036015 - 036023   2009.6

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  • Evolution of carrying capacity in evolution experiments focusing on a single locus on the Escherichia coli chromosome

    Kotaro Mori, Akiko Kashiwagi, Itaru Urabe and Tetsuya Yomo

    BioSystems   95 ( 2 )   114 - 119   2009.2

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  • Construction of Escherichia coli Gene Expression Level Perturbation Collection

    Akiko Kashiwagi, Takahiro Sakurai, Saburo Tsuru, Bei-Wen Ying, Kotaro Mori and Tetsuya Yomo

    Metabolic Engineering   11 ( 1 )   56 - 63   2009.1

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  • Phenotypic plasticity of Escherichia coli at initial stage of symbiosis with Dictyostelium discoideum

    Akito Yamada, Shin-Ichi Matsuyama, Masahiko Todoriki, Akiko Kashiwagi, Itaru Urabe, Tetsuya Yomo

    BioSystems   92   1 - 9   2008.4

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  • An improved physico-chemical model of hybridization on high-density oligonucleotide microarrays

    Naoki Ono, Shingo Suzuki, Chikara Furusawa, Tomoharu Agata, Akiko Kashiwagi, Hiroshi Shimizu and Tetsuya Yomo

    Bioinformatics   24 ( 10 )   1278 - 1285   2008.3

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  • Experimental optimization of probe length to increase the sequence specificity of high-density oligonucleotide microarrays

    Shingo Suzuki, Naoki Ono, Chikara Furusawa, Akiko Kashiwagi and Tetsuya Yomo

    BMC Genomics   8   373   2007.10

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  • Insight into the sequence specificity of a probe on an Affymetrix GeneChip by titration experiments using only one oligonucleotide

    Shingo Suzuki, Chikara Furusawa, Naoki Ono, Akiko Kashiwagi, Itaru Urabe and Tetsuya Yomo

    BIOPHYSICS   3   47 - 56   2007.9

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  • Analysis of Fluctuation in Protein Abundance without Promoter Regulation based on Escherichia coli Continuous Culture

    Tadashi Yamada, Chikara Furusawa, Keisuke Nagahisa, Akiko Kashiwagi, Tetsuya Yomo, and Hiroshi Shimizu

    BioSystems   90 ( 3 )   614 - 622   2007.2

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  • Adaptive Response of a Gene Network to Environmental Changes by Fitness-induced Attractor Selection

    Akiko Kashiwagi, Itaru Urabe, Kunihiko Kaneko and Tetsuya Yomo

    Plos ONE   1 ( 1 )   e49 - e49   2006.12

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  • Inherent Characteristics of Gene Expression for Buffering Environmental Changes

    Takao Suzuki, Akiko Kashiwagi, Itaru Urabe and Tetsuya Yomo

    BIOPHYSICS   2   63 - 70   2006.11

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  • Analysis of fluctuation in gene expression based on continuous culture system

    Tadashi Yamada, Makoto Sadamitsu, Keisuke Nagahisa, Akiko Kashiwagi, Chikara Furusawa, Tetsuya Yomo, and Hiroshi Shimizu

    Bio-ADIT 2006   113 - 127   2006.6

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  • Ubiquity of log-normal distributions in intra-cellular reaction dynamics

    Chikara Furusawa, Takao Suzuki, Akiko Kashiwagi, Tetsuya Yomo and Kunihiko Kaneko

    BIOPHYSICS   1   25 - 31   2005.4

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  • History dependent effect on phenotypic expression of a newly emerged gene

    Takao Suzuki , Akiko Kashiwagi , Kotaro Mori , Itaru Urabe and Tetsuya Yomo

    BioSystems   77 ( 1-3 )   137 - 141   2004.11

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  • Analysis of Cell Population Dynamics in Continuous Culture of Escherichia coli

    Tadashi Yamada, Kouichi.Maeoka, Akiko Kashiwagi, Keisuke Nagahisa,

    Proceeding of Asian Pacific Confederation of Chemical Engineering   3P ( 01 )   087   2004.10

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  • Plasticity of fitness and diversification process during an experimental molecular evolution

    Akiko Kashiwagi, Wataru Noumachi, Masato Katsuno, Mohammad. T. Alam, Itaru Urabe and Tetsuya Yomo

    Journal of Molecular Evolution   52 ( 6 )   502 - 509   2001.6

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  • How small can the difference among competitors be for coexistence to Occur

    Akiko Kashiwagi, Tadashi Kanaya, Tetsuya Yomo, and Itaru Urabe

    Researches on Population Ecology   40 ( 2 )   223 - 226   1998.6

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  • Fate of a mutant emerging at the initial stage of evolution

    Xu Wei.-Zhong., Akiko Kashiwagi, Tetsuya Yomo, and Itaru Urabe

    Researches on Population Ecology   38 ( 2 )   231 - 237   1996.6

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Books

  • Experimental Molecular Evolution Showing Flexibility of Fitness Leading to

    Akiko Kashiwagi, Wataru Noumachi, Masato Katsuno, Mohammad. T. Alam, Itaru Urabe and Tetsuya Yomo( Role: Joint author)

    Springer-Verlag Berlin Heidelberg  2004.4 

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  • シリーズ・ニューバイオフィジックスII 複雑系のバイオフィジックス 第4章 大腸菌を用いた実験室内進化

    柏木 明子,四方 哲也( Role: Joint author)

    共立出版株式会社  2001.8 

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    Language:Japanese Book type:Scholarly book

Review Papers

  • フラスコの中で変異と選択を繰り返す実験進化 酵素の機能改変から生物進化の仮説検証まで

    柏木 明子

    日本農芸化学会誌 化学と生物   4   202 - 203   2020.4

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (scientific journal)   Kind of work:Single Work  

  • RNA バクテリオファージQβ の高温適応実験進化における適応機構

    柏木明子

    (独)日本学術振興会「科研費NEWS」(2018年度VOL.1)   2018.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Kind of work:Single Work  

  • 微生物を用いたフラスコの中での実験進化

    柏木明子

    生産と技術   66 ( 4 )   30 - 32   2014.10

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:社団法人 生産技術振興協会   Kind of work:Single Work  

  • フラスコの中の微生物生態系

    柏木 明子

    日本生物工学会誌   89 ( 7 )   411   2011.7

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:公益社団法人 日本生物工学会   Kind of work:Single Work  

  • 生命システム探求への構成的アプローチにおけるBD FACS™フローサイトメーターの応用

    森 光太郎、角南 武志、伊藤 洋一郎、柏木 明子、四方 哲也

    BD Biosciences Cell Analysis Science Avanzato   4   2009.4

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    Language:Japanese   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:ベクトンディッキンソン   Kind of work:Joint Work  

  • Dynamic Behavior of Cell Distribution in Continuous Culture of Escherichia coli

    Tadashi Yamada, Kohei Maeoka, Akiko Kashiwagi, Keisuke Nagahisa, Chikara Furusawa, Suteaki Shioya, Tetsuya Yomo, Hiroshi Shimizu

    ソフトウエアバイオロジー   4   31 - 36   2005.3

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    Language:English   Publishing type:Article, review, commentary, editorial, etc. (other)   Publisher:化学工学会   Kind of work:Joint Work  

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Awards

  • 長瀬研究振興賞

    2020.04

  • 平成27年度弘前大学学術特別賞 若手優秀論文賞

    2016.02

  • 第1回BIOPHYSICS論文賞

    2012.06

  • Zukerkandl Prize

    2002.01

Social Activities

  • 弘前大学ドリーム講座

    2008.12

  • 弘前大学ドリーム講座

    2007.11