日本化学会

American Chemical Society

THE SOCIETY OF SYNTHETIC ORGANIC CHEMISTRY, JAPAN

PESTICIDE SCIENCE SOCIETY OF JAPAN

JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY

THE CHEMICAL SOCIETY OF JAPAN

"Fruiting Liquid" of Mushroom-Forming Fungi, A Novel Source of Bioactive Compounds - Fruiting-Body Inducer and HIF and Axl Inhibitors.

Wu J, Uchida K, Yoshikawa A, Hashimoto M, Kondo M, Nihei K, Ishii M, Choi JH, Miwa Y, Shoda C, Lee D, Nakai A, Kurihara T, D'Alessandro-Gabazza CN, Toda M, Yasuma T, Gabazza EC, Hirai H, Kawagishi H

Journal of agricultural and food chemistry   71 ( 36 )   13338 - 13345   2023.9

“Fruiting Liquid”of Mushroom-Forming Fungi,A Novel Source of Bioactive Compounds−Fruiting-Body Inducer and HIF and Axl Inhibitors

J. Wu, K. Uchida, A. Yoshikawa, M. Hashimoto, M. Kondo, K. Nihei, M. Ishii, J.-H. Choi, Y. Miwa, C. Shoda, D. Lee, A. Nakai, T. Kurihara, C. N. D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C. Gabazza, H. Hirai, H. Kawagishi

Agricultural Food Chemistry   71 ( 36 )   13338 - 13345   2023.8

HIV-1 Integrase Inhibitor, Dihydroobionin B, and the Investigation of Its Extraordinary Specific Rotation

K. Hashimoto, K. Kimura, K. Ishida, E. Morita, K. Tanaka. M. Hashimoto

Journal of Natural Products   86 ( 9 )   2139 - 2144   2023.8

Pseudo-Enantiomeric Paraphaeolactones and Their Biosynthetic Derivatives from Paraphaeosphaeria sp. KT4192: A Proposition of a Favorskii Rearrangement for Their Biosynthesis

R. Kanehara, Y. Oinuma, H. Maeda, M. Okazaki, K. Konno, K. Tanaka, M. Hashimoto

Journal of Natural Products   86 ( 7 )   1832 - 1843   2023.6

Novel Cyclopropyl Compounds, Cyclopropylvirgines A to G, from the Fruiting Bodies of Amanita Virgineoides

J. Wu, Y. Kamiishi, K. Shimozaki, M. Kondo, M. Hashimoto, J.-H. Choi, C. N D’Alessandro-Gabazza, M. Toda, T. Yasuma, E. C Gabazza, H. Hirai, H. Kawagishi

Bulletin of the Chemical Society of Japan   96 ( 6 )   503 - 509   2023.5

Integrasone Derivatives Isolated from Lepteutypa sp. KT4162 and Their Anti-HIV-1 Integrase Activity

S. Miura, K. Ishida, K. Tanaka, E. Morita and M. Hashimoto

Journal of Natural Products   86 ( 4 )   1019 - 1024   2023.5

Isolation of cyclohumulanoids from Daedaleopsis tricolor and their biosynthesis based on in silico simulations.

R. Kanehara, A. Tonouchi, K. Konno, H. Koshino, M. Hashimoto

Tetrahedron   123   133006   2022.8

Structural Determination, Total Synthesis, and Biological Activity of Iezoside, a Highly Potent Ca2+-ATPase Inhibitor from the Marine Cyanobacterium Leptochromothrix valpauliae

N. Kurisawa, A. Iwasaki, K. Teranuma, S. Dan, C. Toyoshima, M. Hashimoto, Kiyotake Suenaga

Journal of American Chemical Society   144 ( 24 )   11019 - 11032   2022.7

Isolation, Identification, and DFT-based Conformational Analysis of Sesquikarahanadienone and its Congeners from Freshwater Dothideomycetes Neohelicascus aquaticus KT4120

Ayane Hayasaka, Kazuki Hashimoto, Katsuhiro Konno, Kazuaki Tanaka, Masaru Hashimoto

Bulletin of the Chemical Society of Japan   95 ( 5 )   833 - 845   2022.5

Biochemistry-Guided Prediction of the Absolute Configuration of Fungal Reduced Polyketides

Takino, Junya, Kotani, Akari, Ozaki, Taro, Peng, Wenquan, Yu, Jie, Guo, Yian, Mochizuki, Susumu, Akimitsu, Kazuya, Hashimoto, Masaru, Ye, Tao, Minami, Atsushi, Oikawa, Hideaki

Angewandte Chemie International Edition   60 ( 43 )   23403 - 23411   2021.8

Isolation and Structural Elucidation of Novel Fusicoccan Dehydroxypericonicin A from Roussoella sp.

Ayane Hayasaka, Kazuaki Tanaka, and Masaru Hashimoto

Biosci. Biotech. Biochem.   85 ( 8 )   1798 - 1801   2021.8

Semipinacol rearrangement of a bicyclo [7.2. 0] undecane framework into a bicyclo [6.3. 0] undecane skeleton: A model study on the biosynthesis of seiridiasteriscane A

Osamu Ishibashi, Mami Nishiyama, Eunsang Kwon, Masaru Hashimoto, Shigefumi Kuwahara, Masaru Enomoto

Biosci. Biotech. Biochem.   85 ( 7 )   1621 - 1627   2021.7

Cyclohumulanoid Sesquiterpenes from the Culture Broth of the Basidiomycetous Fungus Daedaleopsis tricolor

Ryuhi Kanehara, Akio Tonouchi, Katsuhiro Konno, and Masaru Hashimoto

Molecules   26 ( 14 )   4364   2021.6

Decaspirones and Palmarumycins from Phaeoseptum sp. KT4106: Chirality Reinvestigation of Palmarumycins CP4a and CP5

Ryuhi Kanehara, Ayane Hayasaka, Kota Inose, Takeshi Okamura, Satomi Miura, Kazuaki Tanaka, and Masaru Hashimoto

Tetrahedron Lett.   92   132251   2021.6

Oxidative Ring Contraction by a Multifunctional Dioxygenase Generates the Core Cycloocatadiene in the Biosynthesis of Fungal Dimeric Anhydride Zopfiellin

Tetsuya ShiinaTaro OzakiYusuke MatsuShota NagamineChengwei LiuMasaru HashimotoAtsushi Minami, Hideaki Oikawa

Organic Letters   22 ( 5 )   1997 - 2001   2020.2

Anti-Japanese Encephalitis Virus (JEV) Activity of Triterpenes and Flavonoids from Euphorbia hirta

Wilanfranco C. Tayone, Kotaro Ishida, Simon Goto, Janeth C. Tayone, Masashi Arakawa, Eiji Morita, Masaru Hashimoto

Philipp J. Sci.   149 ( 3 )   603 - 613   2020.2

Identification of neomacrophorins isolated from Trichoderma sp. 1212-03 as proteasome inhibitors.

Uesugi S, Honmura Y, Nishiyama M, Kusakabe K, Tonouchi A, Yamashita T, Hashimoto M, Kimura K-i.

27 ( 24 )   115161   2019.11

DFT calculation–assisted stereo‐structural assignment of arundifungin

Mami Nishiyama Akio Tonouchi Hayato Maeda Masaru Hashimoto

Chirality   32 ( 1 )   17 - 31   2019.11

DFT assisted NMR analysis of natural products

Masaru Hashimoto, Eri Fukushi, Warren Hehre

Bulletin of the Nuclear Magnetic Resonance Society of Japan   10   31 - 41   2019.11

Cyclopericodiol and Novel Chlorinated Melleins Isolated from Periconia macrospinosa KT3863

Kota Inose, Kazuaki Tanaka, Hiroyuki Koshino, Masaru Hashimoto

75 ( 35 )   130470   2019.8

An Efficient Protocol for Accurately Calculating 13C Chemical Shifts of Conformationally Flexible Natural Products: Scope, Assessment and Limitations.

Warren Hehre, Phillip Klunzinger, Bernard Deppmeier, Andy Driessen, Noritaka Uchida, Masaru Hashimoto, Eri Fukushi, Yusuke Takata

J. Nat. Prod.   82 ( 8 )   2299 - 2306   2019.8

Cyclopericodiol and new chlorinated melleins isolated from Periconia macrospinosa KT3863.

Inose K, Tanaka K, Koshino H, Hashimoto, M

Tetrahedron Letters   75 ( 35 )   130470   2019.7

Biosynthetic machinery of 6‐hydroxymellein derivatives leading to cyclohelminthols and palmaenones

Takahiro Ugai, Atsushi MInami, Shizuya Tanaka, Raro Ozaki, Chengwei Liu, Hideyuki Shigemori, Masaru Hashimoto, Hideaki Oikawa

ChemBioChem   20 ( 1 )   1 - 9   2019.6

Neomacrophorin and Premacrophorin Congeners from Trichoderma sp. 1212-03

Mami NIshiyama, Hayato Maeda, Akito Tonouchi, Masaru Hashimoto

75 ( 22 )   2993 - 3000   2019.5

Isolation of Peribysins O, P, and Q from Periconia macrospinosa KT3863 and Configurational Reinvestigation of Peribysin E Diacetate from Periconia byssoides OUPS-N133

2.Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto

Journal of Natural Products   2019.2

Structure-Activity Relationships of Trichothecenes against COLO201 Cells and Cochliobolus miyabeanus: The Role of 12-Epoxide and Macrocyclic Moieties

1.Manami Matsumoto, Mami Nishiyama, Hayato Maeda, Akio Tonouchi, Katsuhiro Konno, Masaru Hashimoto

Bioorganic and Medicinal Chemistry Letters   29   982 - 985   2019.2

Structure of two purple pigments, catechiopyranocyanidins A and B from the seed-coat of the small red bean, Vigna angularis

3.Yoshida, K.; Nagai, N.; Ichikawa, Y.; Goto, M.; Kazuma, K.; Oyama, K.-i.; Koga, K.; Hashimoto, M.; Iuchi, S.; Takaya, Y.; Kondo, T.,

Scientific Reports   9   1484   2019.2

Biosynthetic study of conidiation-inducing factor conidiogenone: heterologous production and cyclization mechanism of a key bifunctional diterpene synthase.

4.Shiina, T.; Nakagawa, K.; Fujisaki, Y.; Ozaki, T.; Liu, C.; Toyomasu, T.; Hashimoto, M.; Koshino, H.; Minami, A.; Kawaide, H.; Oikawa, H.

Biosci. Biotech. Biochem.   83 ( 2 )   192 - 201   2019.2

Isolation of Peribysins O, P, and Q from Periconia macrospinosa KT3863, and Configurational Reinvestigation of Peribysin E Diacetate from Periconia byssoides OUPS-N133

Kota Inose, Kazuaki Tanaka, Takeshi Yamada, Hiroyuki Koshino, Masaru Hashimoto

J. Nat. Prod.   82 ( 4 )   911 - 918   2019

Synthesis of Chiral Nonracemic α-Difluoromethylthio Compounds with Tetrasubstituted Stereogenic Centers via a Palladium-Catalyzed Decarboxylative Asymmetric Allylic Alkylation

Hiroya Kondo, Mayaka Maeno, Kenta Sasaki, Ming Guo, Masaru Hashimoto, Motoo Shiro, Norio Shibata

Organic Letters   20 ( 22 )   7044 - 7048   2018.11

天然物構造決定におけるDFT計算の活用

橋本勝

有機合成化学協会誌   76 ( 8 )   842 - 850   2018.8

リンゴ果実におけるマイコパラサイト現象の生物有機化学

橋本勝

日本農薬学会誌   43 ( 2 )   101 - 108   2018.8

12-Deoxyroridin J and 12-Deoxyepiisororidin E from Calcarisporium arbuscular

Manami Matsumoto, Shizuya Tanaka, Akio Tonouchi, Masaru Hashimoto

Tetrahedron Letters   59 ( 21 )   1992 - 1995   2018.5

Cyclohelminthols Y1-Y4 Metabolites Possessing Two Spirocyclopropanes in their Structure

Shizuya Tanaka, Kazuaki Tanaka, Hayato Maeda, Masaru Hashimoto

Journal of Organic Chemistry   83 ( 10 )   5688 - 5697   2018.5

Stereochemical Correction and Total Structure of Roridin J

Manami Matsumoto, Atsushi Ito, Akio Tonouchi, Masaaki Okazaki, Masaru Hashimoto

Tetrahedron   73 ( 36 )   5430 - 5435   2017.6

Cyclohelminthol X, a Hexa-substituted Spirocyclopropane from Helminthosporium velutinum yone96: Structural Elucidation, Electronic Circular Dichroism Analysis, and Biological Properties

Shizuya Tanaka, Yuna Honmura, Shota Uesugi, Eri Fukushi, Kazuaki Tanaka, Hayato Maeda, Ken-ichi Kimura, Tatsuo Nehira, Masaru Hashimoto

Journal of Organic Chemistry   82 ( 11 )   5574 - 5582   2017.5

Neomacrophorin X, a [4.4.3]Propellane-typed Meroterpenoid from Trichoderma sp. 1212-03

Kazuaki Kusakabe, Yuna Honmura, Shota Uesugi, Akio Tonouchi, Hayato Maeda, Ken-ichi Kimura, Hiroyuki Koshino, and Masaru Hashimoto

Journal of Natural Products   80 ( 5 )   1484 - 1492   2017.4

29 Practical Protocol for Calculationg <SUP>13</SUP>C Chemical Shifts for Conformationally Flexible Natural Products; Scope and Limitations

Warren Hehre, Philip Klunzinger, Bernard Deppmeier, Uchida Noritaka, Hashimoto Masaru, Fukushi Eri, Takata Yusuke

Symposium on the Chemistry of Natural Products, symposium papers   59 ( 0 )   169 - 174   2017

Homopetasinic acid isolated from Diaporthe sp. strain 1308-05

1.Atsushi Ito, Ikuya Kumagai, Miku Maruyama, Hayato Maeda, Akio Tonouchi, Tatsuo Nehira, Ken-ichi Kimura, and Masaru Hashimoto

Tetrahedron Letters   57 ( 10 )   1117 - 1119   2016.1

Isolation, absolute structures, and biological properties of cyclohelminthols I–IV from Helminthosporium velutinum yone96

2.Yuna Honmura, Shota Uesugi, Hayato Maeda, Kazuaki Tanaka, Tatsuo Nehira, Ken-ichi Kimura, Masaaki Okazaki, Masaru Hashimoto

Tetrahedron   72 ( 10 )   1400 - 1405   2016.1

Homojesterones: vinylogous analogues of jesterone from Helminthosporium velutinum TS28

3.Miki Arayama, Shota Uesugi, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Ken-ichi Kimura, Masaru Hashimoto

Tetrahedron Letters   57 ( 7 )   1031 - 1035   2015.12

4.Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto

4.Miki Arayama, Hayato Maeda, Kazuaki Tanaka, Noboru Takada, Tatsuo Nehira, Masaru Hashimoto

Tetrahedron   71 ( 41 )   7900 - 7905   2015.8

Isolation, ECD assisted structural analyses, biosynthetic discussions, and biological activities of epi-cochlioquinones D and its derivatives

2.Miki Arayama, Tatsuo Nehira, Hayato Maeda, Kazuaki Tanaka, Hisashi Miyagawa, Tamio Ueno, Seijiro Hosokawa, Masaru Hashimoto

Tetrahedron   71 ( 29 )   4788 - 4794   2015.5

リンゴ果実上におけるマイコパラサイト現象の分子機構

橋本勝

有機合成化学協会誌   73 ( 3 )   230 - 240   2015.3

Isotopic Differentiation Protocol, a Selective Extraction of C- and N-Terminal Ions in ESI-Ms/Ms De Novo Peptide Sequencing

Mako Fujii, Hiroshi Chiba, Noriko Tamayama, Saki Kanamaru, and Masaru Hashimoto

Natural Products Chemistry & Research   3 ( 1 )   1000164 - 1000164   2015.1

Computation-Assisted Structural Elucidation of Epoxyroussoeone and Epoxyroussoedione Isolated from Roussoella japanensis KT1651

Yuna Honmura, Hiroto Takekawa, Kazuaki Tanaka, Hayato Maeda, Tatsuo Nehira, Warren Hehre, and Masaru Hashimoto

J. Nat. Products   2015

Relative and absolute structure of phomolide C

4.Ito, A.; Maeda, H.; Tonouchi, A.; Hashimoto, M.

Biosci. Biotech. Biochem,   2015

Lambertellin System, the mechanism for fungal replacement of Moniliniafructigena with Lambertellacorni-maris without competitive inhibition on ager media

Akane Hirose, Shinji Kudo, Takanori Murakami, Kazuaki Tanaka, Yukio Harada, Masaru Hashimoto

Bioorg. Med. Chem.   22 ( 8 )   2489 - 2495   2014.3

Neomacrophorin I, II, and III, novel drimenyl cyclohexanes with hydroxylated butanoates from Trichoderma sp. 1212-03

Akane, Hirose, Hayato, Maeda, Akio, Tonouchi, Masaru Hashimoto

Tetrahedron   70 ( 7 )   1458 - 1463   2014.1

Bioorganic studies of the mycoparasitism on apple fruits

Masaru Hashimoto

News Letter on division of biofunctional Chemistry, The Chemical Soxiety of Japan   28 ( 3 )   3 - 6   2013.12

Termination of structural confusion between plipastatin and fengycin

Masaru Hashimoto

Chemistry and Biology   51 ( 12 )   840 - 843   2013.12

7-b- and 10-b-Hydroxylated Congeners of CAF-603; Elucidation of Absolute Configuration of CAF-603 Family, and their SAR Studies in the Antifungal Activity

Hiroto Takekawa, Kazuaki Tanaka, Eri Fukushi, Koichi Matsuo, Tatsuo Nehira, Masaru Hashimoto

Tetrahedron Letters   69 ( 6 )   1047 - 1051   2013.9

Roussoellols A and B, Tetracyclic Fusicoccanes from Roussoella hysterioides

Hiroto Takekawa, Kazuaki Tanaka, Eri Fukushi, Koichi Matsuo, Tatsuo Nehira, Masaru Hashimoto

Journal of Natural Products   76 ( 6 )   1047 - 1051   2013.5

Structural corrections of photinides A, B and their novel derivatives

R. Yasumura; K. Tanaka.; T. Nehira; M. Hashimoto

Tetrahedron   38 ( 23 )   7991 - 7996   2012.6

Termination of the structural confusion between plipastatin A1 and fengycin IX

M. Honma, K. Tanaka, K. Konno, K. Tsuge, T. Okuno, M. Hashimoto

Bioorg. Med. Chem.   20   3793 - 3798   2012.4

Absolute Stereochemistry of Altersolanol A and Alterporriols

S. Kanamaru, M. Honma, T. Murakami, T. Tsushima, S. Kudo, K. Tanaka, K. Nihei, T. Nehira, M. Hashimoto

Chirality   24   137 - 146   2011.12

Absolute Stereochemistry of Novel Isochromanone Derivatives from Leptosphaeria sp. KTC 727

W. C. Tayone, S. Kanamaru, M. Honma, K. Tanaka, T. Nehira, M. Hashimoto

Biosci. Biotech. Biochem,   75 ( 12 )   2390 - 2393   2011.12

A novel bisretinoid of retina is an Adduct on Glycerophosphoetanolamine

K. Yamamoto, K. Yoon, K. Ueda, M. Hashimoto, J. R. Sparrow

Investigative Ophthalmology & Visual Science   52 ( 12 )   9084 - 9090   2011.11

Syntheses of cellotriose and cellotetraose analogues as transition state mimics for mechanistic studies of cellulases

1. S. Noguchi, S. Takemoto, S. Kidokoro, K.. Yamamoto, M. Hashimoto

Bioorg. Med. Chem,   19   3812 - 3830   2011.5

Stereochemical investigations of isochromenone and isobenzofuranone isolated from Leptosphaeria sp. KTC 727

Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira, T.; Hashimoto, M.

J. Nat. Products   74 ( 0 )   425 - 429   2011.3

Stereochemical differentiation in the Simmons-Smith reaction for cyclopropanated glucopyranose derivatives as molecular probes for glycosidases

N. Akiyama, S. Noguchi, M. Hashimoto

Biosci. Biotech. Biochem   75 ( 7 )   1380 - 1382   2011.3

Bunodosine 391: a new analgesic acylamino acid from the venom of the sea anemone Bunodosoma cangicum

4. Wilanfranco T. C.; Honma, M.; Kanamaru S.; Noguchi, S.; Tanaka, K.; Nehira, T.; Hashimoto, M.

J. Nat. Products   74 ( 0 )   378 - 382   2011.3

Synthesis of a trigalacturonic acid analogue mimicking the expected transition state in the glycosidases

Yamamoto, K.; Noguchi, S.; Takada, N.; Miyairi, K.; Hashimoto, M.

Crabohydr. Res.   345 ( 0 )   572 - 585   2009.12

Four Analogues of Spiroleptosphol isolated from Leptosphaeria doliolum

T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M. Hashimoto

Bioorg. Med. Chem.   19 ( 0 )   1122 - 1125   2009.12

Novel Neofusapyrones Isolated from Verticillium dahliae as Potent Antifungal Substances

Honma, M.; Kudo, S.; Takada, N.; Miura, T.; Hashimoto, M.

Bioorg. Med. Chem. Lett.   20 ( 0 )   709 - 712   2009.12

Absolute stereochemistry and conformational analysis of achaetolide isolated from Ophiobolus sp

Tayone, W. C.; Shindo, S.; Murakami, T.; Hashimoto, M.; Tanaka, K.; Takada, N.

Tetrahedron   65 ( 0 )   7464 - 7467   2009.7

Isolation and absolute stereochemistry of optically active sydonic acid from from Glonium sp. (Hysteriales, Ascomycota)"

T. Murakami, T. Tsushima, N. Takada, K. Tanaka, K. Nihei, T. Miura, M. Hashimoto

Bioorg. Med. Chem.   19 ( NA )   492 - 495   2009.3

Spartan Essential Our example introducing that for a class "Molecular modelings"

Masaru Hashimoto

N. A.   26 ( NA )   106 - 112   2009.3

Syntheses of Lambertellols and Their Stable Analogues; Investigation of the Real Active Species in the Mycoparasitism by Lambertella Speciese

Nomiya, M., Murakami, T., Takada, N., Okuno, T., Harada, Y., Hashimoto, M.

J. Org. Chem   73   5039 - 5047   2008.7

Structure and Biosynthesis of Norneolambertellin Produced by Lambertella sp.1346

Hashimoto, M.; Tsushima, T.; Murakami, T.; Nomiya, M.; Takada, N.; Tanaka, K

Bioorg. Med. Chem. Lett.   18 ( 14 )   4228 - 4231   2008.6

Rdc-enhanced NMR spectroscopy in structure elucidation of natural products/small molecules: Sucro-neolambertellin as a testcase

Schuetz, A.; Murakami, T.; Takada, N.; Junker, J.; Hashimoto, M.; Griesinger, C.

Angew. Chem. Int. Ed.   47 ( 11 )   2032 - 2033   2008.2

Stimulation of the Biosynthesis of the Antibiotics Lambertellols by the Mycoparasitic Fungus Lambertella corni-maris under the Acidic Conditions Produced by Its Host Fungus in Vitro

Murakami, T.; Takada, N.; Harada, Y.; Okuno, T.; Hashimoto, M.

Biosci. Biotech. Biochem.   71 ( 7 )   1230 - 1235   2007.7

An RNA polymerase inhibitor, cyclothiazomycin B1, and its isomer.

Hashimoto, M., Murakami, T., Funahashi, K.., Tokunaga, T., Nihei, K.., Okuno, T.,,Kimura, T., Naoki, H., Himeno, H.

Bioorg. Med. Chem,   14 ( 24 )   8259 - 8270   2006.12

Synthetic Studies on Oligo-saccharide Mimics Carrying Sulfur Atoms in the Pyranose ring

Masaru Hashimoto

Journal of Organic Synthetic Chemistry   64 ( 7 )   766 - 777   2006.7

Synthetic Studies of Oligogalacturonate as Molecular Probes for endo-PG1

M. Hashimoto, K., Yamamoto, M. Saito, K. Miyairi, T. Okuno,

ICOB-5 & ISCNP-25 IUPAC International conference on Biodiversity and Natural Products   NA ( NA )   P41 - P41   2006.1

Isolation, structure determination, and biological properties of cyclothiazomycins B1 and B2

T. Murakami, T. Kimura T. Okuno, H. Himeno, M. Hashimoto

ICOB-5 & ISCNP-25 IUPAC International conference on Biodiversity and Natural Products   NA ( NA )   P48 - P48   2006.1

Design, synthesis, and enzymatic property of a sulfur-substituted analogueof trigalacturonic acid

Yamamoto, K., Watanabe, N., Matsuda, H., Oohara, K., Araya, T., Hashimoto, M., Miyairi, K., Okazaki, I., Saito, M., Shimizu, T., Kato, H., Okuno, T.

Bioorg. Med. Chem, Lett.   15 ( 22 )   4932 - 4935   2005.11

Isolation, structure elucidation, preparation,and biological properties of neolambertellin

Murakami, T., Hashimoto, M., Okuno, T.

Bioorg. Med. Chem, Lett.   15 ( 19 )   4185 - 4188   2005.10

Synthetic studies on oligosaccharides composed of 5-thioglucopyranose units

Morii, Y., Matsuda, Y., Ohara, K., Hashimoto, M., Miyairi, K., Okuno, T.

Bioorg. Med. Chem.   13 ( 17 )   5113 - 5144   2005.9

Lambertellol C, a labile and novel biosynthetic congener of lambertellols A and B

Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.

Bioorg. Med. Chem. Lett.,   15 ( 10 )   2587 - 2590   2005.5

Optimization of isotope-labeling conditions for lambertellin based on isotope patterns observed by mass spectrometry

Murakami T., Sasaki A.., Fukushi E., Kawabata J., Hashimoto M., Okuno T.

Bioorg. Med. Chem. Lett.   15 ( 10 )   2591 - 2594   2005.5

Pachyelasides A-D, Novel Molluscicidal Triterpene Saponins from Pachyelasma Tessmannii

Nihei K., YING B.-P., Murakami T., Matsuda H., Hashimoto M. & Kubo I.

J. Agric. Food Chem.,   53 ( 3 )   608 - 613   2005.1

Synthesis of thiosaccharides employing the Pummerer rearrangement of tetrahydrothiopyran oxides

Fujita J., Matsuda H., Yamamoto K., Morii Y., Hashimoto M., Okuno T.& Hashimoto K.

Tetrahedron   60 ( 32 )   6829 - 6851   2004.8

Biosynthesis of Lambertellols Based on the High Specific Incorporation of the 13C-Labeled Acetates and Their Biological Properties

Murakami T., Takahashi Y., Fukushi E., Kawabata J., Hashimoto M., Okuno T.& Harada Y.

J, Am. Chem. Soc.   126 ( 30 )   9214 - 9220   2004.7

Lambertellols A and B, Novel 3,4-Dihydronaphthalen-1(2H)-ones with Spiro-butenolide Produced by Lambertella sp.1346.

Murakami, T., Morikawa, Y., Hashimoto, M., Okuno, T. & Harada, Y.

Org. Lett.   6 ( 2 )   157 - 160   2003.12

Pummerer rearrangement of 1-deoxy-5-thioglucopyranose oxides; novel synthesis of 5-thioglucopyranose derivatives.

Matsuda, H., Fujita, J., Morii, Y., Hashimoto, M., Okuno, T. & Hashimoto, K.

Tetrahedron Letters   44 ( 21 )   4089 - 4093   2003.5

α-Selective Glycosylation with 5-thioglucopyranosyl Donnors; Synthesis of an Isomaltotetraoside mimic Composed of 5-thioglucopyranose Units.

Matsuda, H., Ohara, K., Morii, Y., Hashimoto, M., Miyairi, K. & Okuno, T.

Bioorg. Med. Chem. Lett.   13 ( 21 )   1063 - 1066   2003.4

Synthetic studies of carzinophilin. Part 4: Chemical and biological properties of carzinophilin analogues.

Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima,S.

Tetrahedron   59 ( 17 )   3089 - 3097   2003.4

Synthetic studies of carzinophilin. Part 1: Synthesis of 2-methylidene-1-azabicyclo[3.1.0]hexane systems related to carzinophilin.

Hashimoto, M., Matsumoto, M. & Terashima, S.

Tetrahedron   59 ( 17 )   3019 - 3040   2003.4

Synthetic studies of carzinophilin. Part 2: Synthesis of 3,4-dibenzyloxy-2-methylidene-1-azabicyclo[3.1.0]hexane systems corresponding to the C1-17 fragment of carzinophilin.

Hashimoto, M., Matsumoto, M. & Terashima, S.

Tetrahedron   59 ( 17 )   3041 - 3062   2003.4

Synthetic studies of carzinophilin. Part 3: Synthetic approach toward carzinophilin and successful synthesis of 13-O-desacetyl-12,13-di-O-benzyl-4-O-methylcarzinophilin

Hashimoto, M., Sugiura, M. & Terashima, S.

Tetrahedron   59 ( 17 )   3063 - 3087   2003.4

b-Selective Glycosylation of 5-Thioglucopyranose Derivatives: Synthesis of b-(1-6)Linked 5'-Thioglucopyranosyl Disaccharides.

Ohara, K., Matsuda, H., Hashimoto, M., Miyairi, K. & Okuno, T

Chemistry Letters   2002 ( 00 )   626 - 627   2002.1

Total Synthesis of Both Enantiomers of Dictyochromenol and their (Z)-Isomers.

Aoki, K., Takahashi, M., Hashimoto, M., Okuno, T., Kurata, K. & Suzuki, M.

Biosci. Biotech. Biochem.   66 ( 00 )   1915 - 1924   2002.1

Novel Preparation of (2-Azidomethyl)benzoic Acid and an Application as a Protective Group

Matsuda, H., Hashimoto, M. & Okuno, T.

Syn. Commun.   32 ( 00 )   347 - 345   2002.1

100(P-48) Synthetic Studies on Oligosaccharides Containing Sulfur in the Pyranose Ring

Matsuda Hiroko, Ohara Keiichiro, Fujita Junji, Hashimoto Masaru, Miyairi Kazuo, Okuno Toshikatsu

Symposium on the Chemistry of Natural Products, symposium papers   44 ( 0 )   587 - 592   2002

Fluorescent Pigments if the Retinal Pigment Epithelium and Age-related Macular Degeneration.

Ben-Shabat, S., Craig, P., A, Hashimoto, M., Liu, J., Koji, N. & Sparrow, J.

Bioorg. Med. Chem. Lett.   11 ( 00 )   1533 - 1540   2001.1

Design and Synthesis of a novel Photoaffinity Taxoid as a Potential Probe for the Study of Paclitaxel-microtubules Interactions.

Lin, S., Fang, K., Hashimoto, M., Nakanishi, K. & Ojima, I.

Tetrahedron Lett.,   41 ( 00 )   4287 - 4290   2000.1

A2E, a Lipofuscin Fluorophore, in Human Retinal Pigmented Epithelial Cells in Culture

Sparrow, J., Craig, P., A, Hashimoto, M. & Nakanishi, K.

IVOS   40 ( 00 )   2988 - 1995   2000.1

Enantioselective Binding of an 11-cis-Locked Cyclopropyl Retinal. The Conformation of Retinal in Bovine Rhodopsin

Hashimoto, M. & Fujimoto, Y.

Syn. Commun.   29 ( 00 )   3793 - 3797   1999.1

Preparation and Biological Properties of Biotinylated PhTX Derivatives.

Hashimoto, M., Liu, Y., Fang, K., Li, H.-y. & Nakanishi, K.

Bioorg. Med. Chem.   7 ( NA )   1181 - 1194   1999.1

A Stereoselective Synthesis of 4-O-methyl-13-Desacetyl-12,13-di-O-benzylcarzinophilin.

Hashimoto, M. & Terashima, S.

Heterocycles   47 ( NA )   59 - 64   1998.1

Isolation and One-step Preparation of A2E and Iso-A2E, Fluorophores from Human Retinal Epithelium.

Craig, P., A, Hashimoto, M., Nakanishi, K., Dillon, J. & Sparrow, J.

Proc. Nat. Acd. Sci. USA,   95 ( NA )   14609 - 14613   1998.1

A Bifunctional Photoaffinity Probe for Ligand/Receptor Interaction Studies.

Fang, K.; Hashimoto, M.; Jockusch, S.; Turro, N. J.; Nakanishi, K.

J, Am. Chem. Soc.,   120 ( NA )   8543 - 8544   1998.1

Total Synthesis of an Enantiomeric Pair of Fr900482. 2. Synthesis of the Aromatic and Optically Active Aliphatic Segments.

Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.

Tetrahedron   53 ( NA )   10239 - 10252   1997.1

Total Synthesis of Natural (+)-FR-900482. 2. Efficient Synthesis of the Aromatic and Optically Active Aliphatic Fragments.

Yoshino, T., Nagata, Y., Itoh, E., Hashimoto, M., Katoh, T. & Terashima, S.

Tetrahedron Letters   37 ( NA )   3475 - 3478   1996.1

Novel Synthesis of (+)-Hydantocidin Based on the Plausible Biosynthetic Pathway.

Nakajima, N., Matsumoto, M., Kirihara, M., Hashimoto, M., Katoh, T. & Terashima, S.

Tetrahedron   52 ( NA )   1177 - 1194   1996.1

One-step Synthesis of (5)-Epi-Hydantocidin.

Nakajima, N., Kirihara, M., Matsumoto, M., Hashimoto, M., Katoh, T. & Terashima, S.

Heterocycle   42 ( NA )   503 - 508   1996.1

Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 2. Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine.

Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.

Tetrahedron   50 ( NA )   3905 - 3914   1994.1

Synthesis, Chemical Reactivity, and Cytotoxicity of Carzinophilin Congeners Carrying a 2-(Acylamino-1-alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane System.

Hashimoto, M., Matsumoto, M., Yamada, K. & Terashima, S.

Tetrahedron Letters   35 ( NA )   2207 - 2210   1994.1

A Stereoselective Synthesis of a Novel Model Compound of Carzinophilin Carrying the C6-C13 Unit with Correct Stereochemistry.

Hashimoto, M. & Terashima, S.

Chemistry Letters   1994 ( NA )   1101 - 1104   1994.1

A Novel Synthesis of the C1-C17 Fragment of Carzinophilin.

Hashimoto, M. & Terashima, S.

Tetrahedron Letters   35 ( NA )   9409 - 9412   1994.1

Synthetic Studies on the Key Component of the New Generation of Quinolonecarboxylic Acid, DU-6859. 1. Synthesis of (1R,2S)-2-Fluorocyclopropylamine by the Use of Optical Resolution.

Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.

Tetrahedron   50 ( NA )   3889 - 3904   1994.1

Asymmetric Synthesis of (1R,2S)-2-Fluorocyclopropylamine. the Key Intermediate of the New Generation of quinolonecarboxylic acid, DU-6859.

Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.

Tetrahedron Letters   33 ( NA )   3487 - 3490   1992.1

Chemical Reactivity, and Cytotoxicity of 2-Bis(alkoxycarbonyl)methylidene-1-azabicyclo[3.1.0]hexane Systems Related to Antitumor Antibiotic Carzinophilin A.

Hashimoto, M., Yamada, K. & Terashima, S.

Chemistry Letters   1992 ( NA )   975 - 978   1992.1

Synthesis and Optical Resolution of dl-cis-2-Fluorocyclopropylamine, the Key Component of the New Generation of Quinolonecarboxylic acid, DU-6859.

Tamura, O., Hashimoto, M., Kobayashi, Y., Katoh, T., Nakatani, K., Kamada, M., Hayakawa, I., Akiba, T. & Terashima, S.

TetrahedronLetters   34 ( NA )   3483 - 3486   1992.1

Total Synthesis of the meso-Triterpene Polyether Teurilene.

Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.

J. Org. Chem.   56 ( NA )   2299 - 2311   1991.1

Total Synthesis of (+)-Thyrsiferol, (+)-Thyrsiferyl 23-Acetate, and Teurilene.

Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.

J. Org. Chem.   55 ( NA )   5088 - 5107   1990.1

The Absolute Configuration of 4,6-decadiyne-1,3,8-triol Isolated from Gymnopiliun spectabilis.

Hashimoto, M., Yanagiya, M., Okuno, T. & Shirahama, H.

Bull. Chem. Soc. Jpn.   62 ( NA )   2751 - 2752   1989.1

Total Synthesis of (+)-Thyrsiferol and (+)-Venustatriol

Hashimoto, M., Kan, T., Nozaki, K., Yanagiya, M., Shirahama, H. & Matsumoto, T.

Tetrahedron Letters   29 ( 00 )   1143 - 1144   1988.1

A Short Step Synthesis of Teurilene. Stereocontrolled Sequential Double Cyclization of the C30-Tetraenetetraol to the Tandem Tetrahydrofurane System.

Hashimoto, M., Harigaya, H., Yanagiya, M. & Shirahama, H.

Tetrahedron Letters   29 ( NA )   5947 - 5948   1988.1

Effective Deprotection of 2-(Trimethylsilylethoxy)methylated Alcohols (SEM Ethers). Synthesis of Thyrsiferyl-23 Acetate.

Kan, T., Hashimoto, M., Yanagiya, M. & Shirahama, H.

Tetrahedron Letters   29 ( NA )   5417 - 5418   1988.1

Total Synthesis of meso-Triterpene Ether, Teurilene

Hashimoto, M., Yanagiya, M. & Shirahama, H.

Chemistry Letters   1988 ( 00 )   645 - 646   1988.1

Synthesis of A-B-C-ring Segment of Thyrsiferol: Construction of a Strained Tetrahydropyrane Ring Existing as a Boat Form.

Hashimoto, M., Kan, T., Yanagiya, M., Shirahama, H. & Matsumoto, T.

Tetrahedron Lettres   28   5665 - 5668   1987.1

弘前大学ドリーム講座

2009.08

進学相談会

2009.06

弘前大学ドリーム講座

2007.10