論文 - 葛西 秋宅
-
Nrf2とATF4の相互作用を基盤にした未病気における疾患予防法の開発
葛西 秋宅
BIO Clinica 36 80 - 84 2021年
-
特集 慢性腎臓病・透析患者の酸化ストレス-最新知見と治療展開 2.慢性腎臓病における酸化ストレス進展機序(1) 慢性腎臓病におけるNrf2-Keap1 経路の役割-CKD 治療薬としての期待
伊東 健, Liu Jun, 葛西 秋宅
臨床透析 36 ( 12 ) 1521 - 1527 2020年11月
-
Correction to: Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan.
Maeda Y, Sasaki A, Kasai S, Goto S, Nishio SY, Sawada K, Tokuda I, Itoh K, Usami SI, Matsubara A
Human genome variation 7 ( 1 ) 27 - 27 2020年10月
-
Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan.
Maeda Y, Sasaki A, Kasai S, Goto S, Nishio SY, Sawada K, Tokuda I, Itoh K, Usami SI, Matsubara A.
Hum Genome Var. 2020年09月
-
Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging.
Shimizu S, Mimura J, Hasegawa T, Shimizu E, Imoto S, Tsushima M, Kasai S, Yamazaki H, Ushida Y, Suganuma H, Tomita H, Yamamoto M, Nakaji S, Itoh K.
PLoS One. 2020年08月
-
多層オミックス解析による認知症の早期発見のためのバイオマーカー探索
多田羅 洋太, 中村 智洋, 山嵜 博未, 勝岡 史城, 千葉 満, 三枝 大輔, 葛西 秋宅, 伊東 健
JSBMS Letters 45 ( Suppl. ) 32 - 32 2020年08月
-
Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Yamazaki H, Kasai S, Mimura J, Ye P, Inose-Maruyama A, Tanji K, Wakabayashi K, Mizuno S, Sugiyama F, Takahashi S, Sato T, Ozaki T, Cavener DR, Yamamoto M, Itoh K
PLoS genetics 16 ( 4 ) e1008693 2020年04月
-
Mitochondrial E3 Ubiquitin Ligase Parkin: Relationships with Other Causal Proteins in Familial Parkinson's Disease and Its Substrate-Involved Mouse Experimental Models.
Torii S, Kasai S, Yoshida T, Yasumoto KI, Shimizu S
International journal of molecular sciences 21 ( 4 ) 1202 - 1202 2020年02月
-
ストレス応答性転写因子Nrf2とATF4の相互作用を基盤にした疾患予防・アンチエイジング法の開発
葛西 秋宅
BIO Clinica 35 60 - 64 2020年
-
Deficiency of P62/SQSTM1 Exacerbates Doxorubicin-Induced Cardiac Dysfunction
Michiko Tsushima, Junsei Mimura, Jun Liu, Hiromi Yamazaki, Shuya Kasai, Hirofumi Tomita, Ken Itoh
CIRCULATION 140 2019年11月
-
Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
Junsei Mimura, Atsushi Inose-Maruyama, Shusuke Taniuchi, Kunio Kosaka, Hidemi Yoshida, Hiromi Yamazaki, Shuya Kasai, Nobuhiko Harada, Randal J Kaufman, Seiichi Oyadomari, Ken Itoh
International journal of molecular sciences 20 ( 7 ) 1706 2019年04月
-
Deficiency of protein-L-isoaspartate (D-aspartate) O-methyl-transferase expression under endoplasmic reticulum stress promotes epithelial mesenchymal transition in lung adenocarcinoma.
Masahiro Yamashita, Masahito Ogasawara, Yasushi Kawasaki, Miyuki Niisato, Heisuke Saito, Shuya Kasai, Chihaya Maesawa, Makoto Maemondo, Kohei Yamauchi
Oncotarget 9 ( 17 ) 13287 - 13300 2018年03月
-
Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease.
Shuya Kasai, Junsei Mimura, Taku Ozaki, Ken Itoh
Frontiers in veterinary science 5 242 - 242 2018年
-
Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2.
Shuya Kasai, Mary J E Richardson, Satoru Torii, Ken-Ichi Yasumoto, Hiroki Shima, Kazuhiko Igarashi, Ken Itoh, Kazuhiro Sogawa, Kazutaka Murayama
The FEBS journal 284 ( 23 ) 4115 - 4127 2017年12月
-
Bcl-2/Bcl-xL inhibitor ABT-737 sensitizes pancreatic ductal adenocarcinoma to paclitaxel-induced cell death.
Shuya Kasai, Takuya Sasaki, Ayano Watanabe, Masao Nishiya, Shinji Yasuhira, Masahiko Shibazaki, Chihaya Maesawa
Oncology letters 14 ( 1 ) 903 - 908 2017年07月
-
Conformational changes in inhibitory PAS domain protein associated with binding of HIF-1α and Bcl-xL in living cells.
Shuya Kasai, Shinji Kajimoto, Yuma Ito, Tomo Saito, Ken-Ichi Yasumoto, Makio Tokunaga, Kumiko Sakata-Sogawa, Hiroshi Fukumura, Kazuhiro Sogawa
Journal of biochemistry 161 ( 3 ) 291 - 296 2017年03月
-
NAD(P)H: Quinone Oxidoreductase-1 Expression Sensitizes Malignant Melanoma Cells to the HSP90 Inhibitor 17-AAG
Shuya Kasai, Nobuyuki Arakawa, Ayaka Okubo, Wataru Shigeeda, Shinji Yasuhira, Tomoyuki Masuda, Toshihide Akasaka, Masahiko Shibazaki, Chihaya Maesawa
PLOS ONE 11 ( 4 ) e0153181 2016年04月
-
Temporal expression in rats of receptor tyrosine kinase Tie2 during early wound healing after tooth extraction
Hirotaka Sato, Shuya Kasai, Chihaya Maesawa
JOURNAL OF ORAL SCIENCE 57 ( 4 ) 313 - 318 2015年12月
-
Inhibitory PAS domain protein is a substrate of PINK1 and Parkin and mediates cell death in a Parkinson's disease model.
S Kasai, S Torii, A Kakita, K Sogawa
Cell death & disease 6 e1886 - e1886 2015年09月
-
Nucleus accumbens associated 1 is recruited within the promyelocytic leukemia nuclear body through SUMO modification.
Yoshinori Tatemichi, Masahiko Shibazaki, Shinji Yasuhira, Shuya Kasai, Hiroshi Tada, Hiroki Oikawa, Yuji Suzuki, Yasuhiro Takikawa, Tomoyuki Masuda, Chihaya Maesawa
Cancer science 106 ( 7 ) 848 - 856 2015年07月