Papers - TOKI TSUTOMU
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[The molecular mechanism of leukemogenesis in Down syndrome-related acute megakaryocytic leukemia].
Ito E, Toki T
Nihon rinsho. Japanese journal of clinical medicine 65 Suppl 1 136 - 140 2007.1
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Development of acute megakaryoblastic leukemia from a minor clone in a Down syndrome patient with clinically overt transient myeloproliferative disorder
Gang Xu, Koji Kato, Tsutomu Toki, Yoshihiro Takahashi, Kiminori Terui, Etsuro Ito
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY 28 ( 10 ) 696 - 698 2006.10
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Physical association of the patient-specific GATA1 mutants with RUNX1 in acute megakaryoblastic leukemia accompanying Down syndrome.
Xu G, Kanezaki R, Toki T, Watanabe S, Takahashi Y, Terui K, Kitabayashi I, Ito E.
Leukemia 20 ( 6 ) 1002 - 1008 2006.6
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Cloning and Characterization of the Novel Chimeric Gene p53/FXR2 in the Acute Megakaryoblastic Leukemia Cell Line CMK11-5
Kanezaki Rika, Toki Tsutomu, Xu Gang, Narayanan Ramswamy, Ito Etsuro
The Tohoku Journal of Experimental Medicine 209 ( 3 ) 169 - 180 2006
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JAK2 Val617Phe activating tyrosine kinase mutation in juvenile myelomonocytic leukemia.
Tono C, Xu G, Toki T, Takahashi Y, Sasaki S, Terui K, Ito E.
Leukemia 19 ( 10 ) 1843 - 1844 2005.10
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Roxithromycin is an inhibitor of human coronary artery smooth muscle cells proliferation: a potential ability to prevent coronary heart disease
H Tomita, T Osanai, T Toki, N Maeda, R Murakami, ZN Chen, H Yamabe, H Osawa, M Yasujima, K Okumura
ATHEROSCLEROSIS 182 ( 1 ) 87 - 95 2005.9
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The proto-oncogene ERG in megakaryoblastic leukemias
L Rainis, T Toki, JE Pimanda, E Rosenthal, K Machol, S Strehl, B Gottgens, E Ito, S Izraeli
CANCER RESEARCH 65 ( 17 ) 7596 - 7602 2005.9
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Troglitazone and 15-deoxy-Delta(12,14)-prostaglandin J(2) inhibit shear-induced coupling factor 6 release in endothelial cells
H Tomita, T Osanai, T Toki, S Sasaki, N Maeda, R Murakami, K Magota, M Yasujima, K Okumura
CARDIOVASCULAR RESEARCH 67 ( 1 ) 134 - 141 2005.7
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KCNJ2 mutation in intractable ventricular arrhythmia with Andersen's syndrome.
Takahashi T, Tandai S, Toki T, Sato T, Eto S, Sato A, Ueda T, Sato S, Ichinose K, Ito E, Yonesaka S
Pediatrics international : official journal of the Japan Pediatric Society 47 ( 2 ) 220 - 223 2005.4
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Transgenic expression of BACH1 transcription factor results in megakaryocytic impairment
T Toki, F Katsuoka, F Kanezaki, G Xu, H Kurotaki, JY Sun, T Kamio, S Watanabe, S Tandai, K Terui, S Yagihashi, N Komatsu, K Igarashi, M Yamamoto, E Ito
BLOOD 105 ( 8 ) 3100 - 3108 2005.4
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The GATA1 mutation in an adult patient with acute megakaryoblastic leukemia not accompanying Down syndrome.
Harigae H, Xu G, Sugawara T, Ishikawa I, Toki T, Ito E
Blood 103 ( 8 ) 3242 - 3243 2004.4
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21q11-21領域からの一過性骨髄異常増殖症の原因遺伝子単離の試み
石崎典子, 金崎里香, 土岐力, 伊藤悦朗
弘前医学 55 ( 3-4 ) 83 - 94 2004.3
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Fetal origin of the GATA1 mutation in identical twins with transient myeloproliferative disorder and acute megakaryoblastic leukemia accompanying Down syndrome.
Shimada A, Xu G, Toki T, Kimura H, Hayashi Y, Ito E
Blood 103 ( 1 ) 366 2004.1
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A trial of isolating the novel genes on 21q11-21 to elucidate the gene responsible for transient abnormal myelopoiesis
Ishizaki Noriko, Kanezaki Rika, Toki Tsutomu, Ito Etsuro
Hirosaki Medical Journal 55 ( 3-4 ) 83 - 94 2004
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Three novel mutations of the fibrillin-1 gene and ten single nucleotide polymorphisms of the fibrillin-3 gene in Marfan syndrome patients
Tomomi Uyeda, Toru Takahashi, Shuji Eto, Takumi Sato, Gang Xu, Rika Kanezaki, Tsutomu Toki, Susumu Yonesaka, Etsuro Ito
Journal of Human Genetics 49 ( 8 ) 404 - 407 2004
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B-cell-specific transcription factor BACH2 modifies the cytotoxic effects of anticancer drugs.
Kamio T, Toki T, Kanezaki R, Sasaki S, Tandai S, Terui K, Ikebe D, Igarashi K, Ito E
Blood 102 ( 9 ) 3317 - 3322 2003.11
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Frequent mutations in the GATA-1 gene in the transient myeloproliferative disorder of Down syndrome
G Xu, M Nagano, R Kanezaki, T Toki, Y Hayashi, T Taketani, T Taki, T Mitui, K Koike, K Kato, M Imaizumi, Sekine, I, Y Ikeda, R Hanada, M Sako, K Kudo, S Kojima, O Ohneda, M Yamamoto, E Ito
BLOOD 102 ( 8 ) 2960 - 2968 2003.10
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Glycogen synthase kinase-3 beta phosphorylates synphilin-1 in vitro
K Tanji, T Toki, W Tamo, T Imaizumi, T Matsumiya, F Mori, H Takahashi, K Satoh, K Wakabayashi
NEUROPATHOLOGY 23 ( 3 ) 199 - 202 2003.9
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B Cell Specific Transcription Factor BACH2 Negatively Regulates Expression of BCL-2 Related A1 Gene
TANDAI Satoru, SATO Hideko, KANEZAKI Rika, TOKI Tsutomu, IGARASHI Kazuhiko, ITO Etsuro
The Hirosaki medical journal 54 ( 1 ) 8 - 20 2002
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Transcription factor BACH1 is recruited to the nucleus by its novel alternative spliced isoform.
R Kanezaki, T Toki, M Yokoyama, K Yomogida, K Sugiyama, M Yamamoto, K Igarashi, E Ito
The Journal of biological chemistry 276 ( 10 ) 7278 - 7284 2001.3