論文 - 伊東 健
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Multiomics and artificial intelligence enabled peripheral blood-based prediction of amnestic mild cognitive impairment
Tatara Y, Yamazaki H, Katsuoka F, Chiba M, Saigusa D, Kasai S, Nakamura T, Inoue J, Aoki Y, Shoji M, Motoike IN, Tamada Y, Hashizume K, Shoji M, Kinoshita K, Murashita K, Nakaji S, Yamamoto M, Itoh K
71 ( 1 ) 103367 - 103367 2022年10月
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Machine learning diagnosis by immunoglobulin N-glycan signatures for precision diagnosis of urological diseases.
Iwamura H, Mizuno K, Akamatsu S, Hatakeyama S, Tobisawa Y, Narita S, Narita T, Yamashita S, Kawamura S, Sakurai T, Fujita N, Kodama H, Noro D, Kakizaki I, Nakaji S, Itoh K, Tsuchiya N, Ito A, Habuchi T, Ohyama C, Yoneyama T
Cancer science 113 ( 7 ) 2434 - 2445 2022年07月
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Sulforaphane Increase Mitochondrial Biogenesis-Related Gene Expression in the Hippocampus and Suppresses Age-Related Cognitive Decline in Mice
Shimizu S, Kasai S, Yamazaki H, Tatara Y, Mimura J, Engler MJ, Tanji K, Nikaido Y, Inoue T, Suganuma H, Wakabayashi K, Itoh K
23 ( 15 ) 2022年07月
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Impact of salivary and pancreatic amylase gene copy numbers on diabetes, obesity, and functional profiles of microbiome in Northern Japanese population.
Hasegawa T, Kakuta M, Yamaguchi R, Sato N, Mikami T, Murashita K, Nakaji S, Itoh K, Imoto S
Scientific reports 12 ( 1 ) 7628 - 7628 2022年05月
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Inducible Systemic <i>Gcn1</i> Deletion in Mice Leads to Transient Body Weight Loss upon Tamoxifen Treatment Associated with Decrease of Fat and Liver Glycogen Storage
Jun Liu, Shuya Kasai, Yota Tatara, Hiromi Yamazaki, Junsei Mimura, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Sato Tsubasa, Taku Ozaki, Kunikazu Tanji, Koichi Wakabayashi, Hayato Maeda, Hiroki Mizukami, Yasuhiro Shinkai, Yoshito Kumagai, Hirofumi Tomita, Ken Itoh
International Journal of Molecular Sciences 23 ( 6 ) 2022年03月
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Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project.
Miura S, Sasaki A, Kasai S, Sugawara T, Maeda Y, Goto S, Kasai T, Shimizume N, Jung S, Iwane T, Itoh K, Matsubara A
Journal of human genetics 67 ( 6 ) 369 - 375 2022年01月
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Telomere Length and Arterial Stiffness Reflected by Brachial-Ankle Pulse Wave Velocity: A Population-Based Cross-Sectional Study.
Wai KM, Kaori S, Itoh K, Shinya O, Uchikawa Y, Hayashi S, Shiraki A, Murashita K, Nakaji S, Ihara K
Journal of personalized medicine 11 ( 12 ) 2021年12月
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Distinct Regulations of <i>HO-1</i> Gene Expression for Stress Response and Substrate Induction.
Zhang A, Suzuki T, Adachi S, Naganuma E, Suzuki N, Hosoya T, Itoh K, Sporn MB, Yamamoto M
Molecular and cellular biology 41 ( 11 ) e0023621 2021年10月
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Age-Related Cognitive Decline and Prevalence of Mild Cognitive Impairment in the Iwaki Health Promotion Project.
Nakahata N, Nakamura T, Kawarabayashi T, Seino Y, Ichii S, Ikeda Y, Amari M, Takatama M, Murashita K, Ihara K, Itoh K, Nakaji S, Shoji M
Journal of Alzheimer's disease : JAD 84 ( 3 ) 1233 - 1245 2021年10月
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多層オミックスと機械学習による軽度認知障害の予測モデルの構築
多田羅 洋太, 中村 智洋, 千葉 満, 三枝 大輔, 山嵜 博未, 勝岡 史城, 葛西 秋宅, 川瀬 倫子, 本間 リナ, 松田 りら, 藤本 哲太, 荘司 美穂, 元池 育子, 玉田 嘉紀, 橋爪 克仁, 東海林 幹夫, 木下 賢吾, 伊東 健
Dementia Japan 35 ( 4 ) 660 - 660 2021年10月
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Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis.
Sugawara M, Abe T, Kasai S, Itoh K, Ozaki T
Biochemistry and biophysics reports 27 101101 - 101101 2021年09月
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Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice.
Ekuban FA, Zong C, Takikawa M, Morikawa K, Sakurai T, Ichihara S, Itoh K, Yamamoto M, Ohsako S, Ichihara G
Toxicology 456 152785 - 152785 2021年05月
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Health improvement framework for actionable treatment planning using a surrogate Bayesian model.
中村 和貴, 小島 諒介, 内野 詠一郎, 尾野 亘, 柳田 素子, 村下 公一, 伊東 健, 中路 重之, 奥野 恭史
Nature communications 12 ( 1 ) 3088 - 3088 2021年05月
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Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study.
Yamamoto H, Suzuki M, Matsuta R, Sasaki K, Kang MI, Kami K, Tatara Y, Itoh K, Nakaji S
Metabolites 11 ( 5 ) 314 - 314 2021年05月
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Characterization of mitochondrial calpain-5.
Chukai Y, Iwamoto T, Itoh K, Tomita H, Ozaki T
Biochimica et biophysica acta. Molecular cell research 1868 ( 5 ) 118989 - 118989 2021年04月
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Association between Serum Concentration of Carotenoid and Visceral Fat.
Matsumoto M, Suganuma H, Ozato N, Shimizu S, Katashima M, Katsuragi Y, Mikami T, Itoh K, Nakaji S
Nutrients 13 ( 3 ) 912 2021年03月
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The CD36 Ligand-Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress.
Dorion MF, Mulumba M, Kasai S, Itoh K, Lubell WD, Ong H
Oxidative medicine and cellular longevity 2021 6691402 - 6691402 2021年03月
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Fe<sub>3</sub>O<sub>4</sub>-PEG-PLGAの経気道曝露による野生型およびNrf2欠損マウスの肺への影響の評価
佐藤 春恵, 宗 才, Stéphanie DEVINEAU, Claire MCCORD, 市原 佐保子, Oliver BROOKES, Frederick Adams EKUBAN, 伊東 健, 山本 雅之, Sonja BOLAND, Armelle BAEZA-SQUIBAN, 市原 学
日本毒性学会学術年会 48.1 ( 0 ) P-32S 2021年
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JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.
Máté János Engler, Junsei Mimura, Shun Yamazaki, Ken Itoh
FEBS open bio 10 ( 12 ) 2771 - 2779 2020年12月
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特集 慢性腎臓病・透析患者の酸化ストレス-最新知見と治療展開 2.慢性腎臓病における酸化ストレス進展機序(1) 慢性腎臓病におけるNrf2-Keap1 経路の役割-CKD 治療薬としての期待
伊東 健, Liu Jun, 葛西 秋宅
臨床透析 36 ( 12 ) 1521 - 1527 2020年11月