論文 - 伊東 健
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The CD36 Ligand-Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress.
Dorion MF, Mulumba M, Kasai S, Itoh K, Lubell WD, Ong H
Oxidative medicine and cellular longevity 2021 6691402 - 6691402 2021年03月
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Fe<sub>3</sub>O<sub>4</sub>-PEG-PLGAの経気道曝露による野生型およびNrf2欠損マウスの肺への影響の評価
佐藤 春恵, 宗 才, Stéphanie DEVINEAU, Claire MCCORD, 市原 佐保子, Oliver BROOKES, Frederick Adams EKUBAN, 伊東 健, 山本 雅之, Sonja BOLAND, Armelle BAEZA-SQUIBAN, 市原 学
日本毒性学会学術年会 48.1 ( 0 ) P-32S 2021年
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JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.
Máté János Engler, Junsei Mimura, Shun Yamazaki, Ken Itoh
FEBS open bio 10 ( 12 ) 2771 - 2779 2020年12月
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特集 慢性腎臓病・透析患者の酸化ストレス-最新知見と治療展開 2.慢性腎臓病における酸化ストレス進展機序(1) 慢性腎臓病におけるNrf2-Keap1 経路の役割-CKD 治療薬としての期待
伊東 健, Liu Jun, 葛西 秋宅
臨床透析 36 ( 12 ) 1521 - 1527 2020年11月
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Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan.
Yasunori Maeda, Akira Sasaki, Shuya Kasai, Shinichi Goto, Shin-Ya Nishio, Kaori Sawada, Itoyo Tokuda, Ken Itoh, Shin-Ichi Usami, Atsushi Matsubara
Human genome variation 7 ( 1 ) 27 - 27 2020年09月
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Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging.
Sunao Shimizu, Junsei Mimura, Takanori Hasegawa, Eigo Shimizu, Seiya Imoto, Michiko Tsushima, Shuya Kasai, Hiromi Yamazaki, Yusuke Ushida, Hiroyuki Suganuma, Hirofumi Tomita, Masayuki Yamamoto, Shigeyuki Nakaji, Ken Itoh
PloS one 15 ( 8 ) e0236834 - e0236834 2020年08月
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Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness.
Mai Matsumoto, Naoko Waki, Hiroyuki Suganuma, Ippei Takahashi, Sizuka Kurauchi, Kahori Sawada, Itoyo Tokuda, Mina Misawa, Masataka Ando, Ken Itoh, Kazushige Ihara, Shigeyuki Nakaji
Nutrients 12 ( 8 ) e2310 - e2310 2020年07月
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Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice.
Yoshikazu Yokono, Kenji Hanada, Masato Narita, Yota Tatara, Yousuke Kawamura, Naotake Miura, Kazutaka Kitayama, Masamichi Nakata, Masashi Nozaka, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Ken Itoh, Hirofumi Tomita
Journal of the American Heart Association 9 ( 12 ) e015616 - e015616 2020年06月
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Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh
PLoS genetics 16 ( 4 ) e1008693 - e1008693 2020年04月
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Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease.
Tsushima M, Liu J, Hirao W, Yamazaki H, Tomita H, Itoh K
Archives of pharmacal research 43 ( 3 ) 286 - 296 2020年03月
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マウスにおけるNrf2の欠損はアクリルアミドの神経毒性に対する感受性を高める
Frederick Adams EKUBAN, 宗 才, 瀧川 円賀, 森川 浩太, 櫻井 敏博, 市原 佐保子, 伊東 健, 山本 雅之, 大迫 誠一郎, 市原 学
日本毒性学会学術年会 47.1 ( 0 ) P-28E 2020年
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Nrf2 in the Regulation of Endothelial Cell Homeostasis During Inflammation
Yamazaki, H., Itoh, K.
Progress in Inflammation Research 85 2020年
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Health improvement framework for planning actionable treatment process using surrogate Bayesian model.
Kazuki Nakamura, Ryosuke Kojima, Eiichiro Uchino, Koichi Murashita, Ken Itoh, Shigeyuki Nakaji, Yasushi Okuno
CoRR abs/2010.16087 2020年
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Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles.
Radwa Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Cai Zong, Ken Itoh, Masayuki Yamamoto, Ahmed Ali Elsayed, Soheir El-Bestar, Emily Kamel, Gaku Ichihara
Particle and fibre toxicology 16 ( 1 ) 47 - 47 2019年12月
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定量的プロテオミクス解析による急性期放射線骨髄障害の重症化リスク因子の探索
多田羅 洋太, 門前 暁, 伊東 健
日本生化学会大会プログラム・講演要旨集 92回 [3P - 307] 2019年09月
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Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
Junsei Mimura, Atsushi Inose-Maruyama, Shusuke Taniuchi, Kunio Kosaka, Hidemi Yoshida, Hiromi Yamazaki, Shuya Kasai, Nobuhiko Harada, Randal J Kaufman, Seiichi Oyadomari, Ken Itoh
International journal of molecular sciences 20 ( 7 ) 1706 2019年04月
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Increase of Tumor Infiltrating γδ T-cells in Pancreatic Ductal Adenocarcinoma Through Remodeling of the Extracellular Matrix by a Hyaluronan Synthesis Suppressor, 4-Methylumbelliferone.
Akiko Suto, Daisuke Kudo, Eri Yoshida, Hayato Nagase, Shinichiro Suto, Junsei Mimura, Ken Itoh, Kenichi Hakamada
Pancreas 48 ( 2 ) 292 - 298 2019年02月
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Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control.
Shuya Kasai, Hiromi Yamazaki, Kunikazu Tanji, Máté János Engler, Tomoh Matsumiya, Ken Itoh
Journal of clinical biochemistry and nutrition 64 ( 1 ) 1 - 12 2019年01月
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Aging and APOE-e4 are determinative factors of plasma Ab42 levels.
Takumi Nakamura, Takeshi Kawarabayashi, Yusuke Seino, Mie Hirohata, Naoko Nakahata, Sakiko Narita, Ken Itoh, Shigeyuki Nakaji, Mikio Shoji
Annals of clinical and translational neurology 5 ( 10 ) 1184 - 1191 2018年10月
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C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.
Sharadha Dayalan Naidu, Aki Muramatsu, Ryota Saito, Soichiro Asami, Tadashi Honda, Tomonori Hosoya, Ken Itoh, Masayuki Yamamoto, Takafumi Suzuki, Albena T Dinkova-Kostova
Scientific reports 8 ( 1 ) 8037 - 8037 2018年05月