論文 - 伊東 健
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多層オミックスと機械学習による軽度認知障害の予測モデルの構築
多田羅 洋太, 中村 智洋, 千葉 満, 三枝 大輔, 山嵜 博未, 勝岡 史城, 葛西 秋宅, 川瀬 倫子, 本間 リナ, 松田 りら, 藤本 哲太, 荘司 美穂, 元池 育子, 玉田 嘉紀, 橋爪 克仁, 東海林 幹夫, 木下 賢吾, 伊東 健
Dementia Japan 35 ( 4 ) 660 - 660 2021年10月
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Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis.
Sugawara M, Abe T, Kasai S, Itoh K, Ozaki T
Biochemistry and biophysics reports 27 101101 - 101101 2021年09月
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Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice.
Ekuban FA, Zong C, Takikawa M, Morikawa K, Sakurai T, Ichihara S, Itoh K, Yamamoto M, Ohsako S, Ichihara G
Toxicology 456 152785 - 152785 2021年05月
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Health improvement framework for actionable treatment planning using a surrogate Bayesian model.
中村 和貴, 小島 諒介, 内野 詠一郎, 尾野 亘, 柳田 素子, 村下 公一, 伊東 健, 中路 重之, 奥野 恭史
Nature communications 12 ( 1 ) 3088 - 3088 2021年05月
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Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study.
Yamamoto H, Suzuki M, Matsuta R, Sasaki K, Kang MI, Kami K, Tatara Y, Itoh K, Nakaji S
Metabolites 11 ( 5 ) 314 - 314 2021年05月
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Characterization of mitochondrial calpain-5.
Chukai Y, Iwamoto T, Itoh K, Tomita H, Ozaki T
Biochimica et biophysica acta. Molecular cell research 1868 ( 5 ) 118989 - 118989 2021年04月
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Association between Serum Concentration of Carotenoid and Visceral Fat.
Matsumoto M, Suganuma H, Ozato N, Shimizu S, Katashima M, Katsuragi Y, Mikami T, Itoh K, Nakaji S
Nutrients 13 ( 3 ) 912 2021年03月
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The CD36 Ligand-Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress.
Dorion MF, Mulumba M, Kasai S, Itoh K, Lubell WD, Ong H
Oxidative medicine and cellular longevity 2021 6691402 - 6691402 2021年03月
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Fe<sub>3</sub>O<sub>4</sub>-PEG-PLGAの経気道曝露による野生型およびNrf2欠損マウスの肺への影響の評価
佐藤 春恵, 宗 才, Stéphanie DEVINEAU, Claire MCCORD, 市原 佐保子, Oliver BROOKES, Frederick Adams EKUBAN, 伊東 健, 山本 雅之, Sonja BOLAND, Armelle BAEZA-SQUIBAN, 市原 学
日本毒性学会学術年会 48.1 ( 0 ) P-32S 2021年
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JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.
Máté János Engler, Junsei Mimura, Shun Yamazaki, Ken Itoh
FEBS open bio 10 ( 12 ) 2771 - 2779 2020年12月
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特集 慢性腎臓病・透析患者の酸化ストレス-最新知見と治療展開 2.慢性腎臓病における酸化ストレス進展機序(1) 慢性腎臓病におけるNrf2-Keap1 経路の役割-CKD 治療薬としての期待
伊東 健, Liu Jun, 葛西 秋宅
臨床透析 36 ( 12 ) 1521 - 1527 2020年11月
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Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan.
Yasunori Maeda, Akira Sasaki, Shuya Kasai, Shinichi Goto, Shin-Ya Nishio, Kaori Sawada, Itoyo Tokuda, Ken Itoh, Shin-Ichi Usami, Atsushi Matsubara
Human genome variation 7 ( 1 ) 27 - 27 2020年09月
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Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging.
Sunao Shimizu, Junsei Mimura, Takanori Hasegawa, Eigo Shimizu, Seiya Imoto, Michiko Tsushima, Shuya Kasai, Hiromi Yamazaki, Yusuke Ushida, Hiroyuki Suganuma, Hirofumi Tomita, Masayuki Yamamoto, Shigeyuki Nakaji, Ken Itoh
PloS one 15 ( 8 ) e0236834 - e0236834 2020年08月
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Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness.
Mai Matsumoto, Naoko Waki, Hiroyuki Suganuma, Ippei Takahashi, Sizuka Kurauchi, Kahori Sawada, Itoyo Tokuda, Mina Misawa, Masataka Ando, Ken Itoh, Kazushige Ihara, Shigeyuki Nakaji
Nutrients 12 ( 8 ) e2310 - e2310 2020年07月
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Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice.
Yoshikazu Yokono, Kenji Hanada, Masato Narita, Yota Tatara, Yousuke Kawamura, Naotake Miura, Kazutaka Kitayama, Masamichi Nakata, Masashi Nozaka, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Ken Itoh, Hirofumi Tomita
Journal of the American Heart Association 9 ( 12 ) e015616 - e015616 2020年06月
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Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh
PLoS genetics 16 ( 4 ) e1008693 - e1008693 2020年04月
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Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease.
Tsushima M, Liu J, Hirao W, Yamazaki H, Tomita H, Itoh K
Archives of pharmacal research 43 ( 3 ) 286 - 296 2020年03月
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マウスにおけるNrf2の欠損はアクリルアミドの神経毒性に対する感受性を高める
Frederick Adams EKUBAN, 宗 才, 瀧川 円賀, 森川 浩太, 櫻井 敏博, 市原 佐保子, 伊東 健, 山本 雅之, 大迫 誠一郎, 市原 学
日本毒性学会学術年会 47.1 ( 0 ) P-28E 2020年
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Nrf2 in the Regulation of Endothelial Cell Homeostasis During Inflammation
Yamazaki, H., Itoh, K.
Progress in Inflammation Research 85 2020年
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Health improvement framework for planning actionable treatment process using surrogate Bayesian model.
Kazuki Nakamura, Ryosuke Kojima, Eiichiro Uchino, Koichi Murashita, Ken Itoh, Shigeyuki Nakaji, Yasushi Okuno
CoRR abs/2010.16087 2020年