Papers - ITOH KEN
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Association of mitochondrial DNA haplogroup and hearing impairment with aging in Japanese general population of the Iwaki Health Promotion Project.
Shiori Miura, Akira Sasaki, Shuya Kasai, Takayuki Sugawara, Yasunori Maeda, Shinichi Goto, Takashi Kasai, Nami Shimizume, Songee Jung, Takuro Iwane, Ken Itoh, Atsushi Matsubara
Journal of human genetics 67 ( 6 ) 369 - 375 2022.1
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Telomere Length and Arterial Stiffness Reflected by Brachial–Ankle Pulse Wave Velocity: A Population-Based Cross-Sectional Study
Kyi Mar Wai, Sawada Kaori, Ken Itoh, Okuyama Shinya, Yuka Uchikawa, Sakura Hayashi, Akiko Shiraki, Koichi Murashita, Shigeyuki Nakaji, Kazushige Ihara
Journal of Personalized Medicine 11 ( 12 ) 2021.12
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Distinct Regulations of HO-1 Gene Expression for Stress Response and Substrate Induction.
Anqi Zhang, Takafumi Suzuki, Saki Adachi, Eriko Naganuma, Norio Suzuki, Tomonori Hosoya, Ken Itoh, Michael B Sporn, Masayuki Yamamoto
Molecular and cellular biology 41 ( 11 ) e0023621 2021.10
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Age-Related Cognitive Decline and Prevalence of Mild Cognitive Impairment in the Iwaki Health Promotion Project.
Naoko Nakahata, Takumi Nakamura, Takeshi Kawarabayashi, Yusuke Seino, Sadanobu Ichii, Yoshio Ikeda, Masakuni Amari, Masamitsu Takatama, Koichi Murashita, Kazunari Ihara, Ken Itoh, Shigeyuki Nakaji, Mikio Shoji
Journal of Alzheimer's disease : JAD 84 ( 3 ) 1233 - 1245 2021.10
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多層オミックスと機械学習による軽度認知障害の予測モデルの構築
多田羅 洋太, 中村 智洋, 千葉 満, 三枝 大輔, 山嵜 博未, 勝岡 史城, 葛西 秋宅, 川瀬 倫子, 本間 リナ, 松田 りら, 藤本 哲太, 荘司 美穂, 元池 育子, 玉田 嘉紀, 橋爪 克仁, 東海林 幹夫, 木下 賢吾, 伊東 健
Dementia Japan 35 ( 4 ) 660 - 660 2021.10
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Calpain-1 C2L domain peptide protects mouse hippocampus-derived neuronal HT22 cells against glutamate-induced oxytosis.
Mayu Sugawara, Takumi Abe, Shuya Kasai, Ken Itoh, Taku Ozaki
Biochemistry and biophysics reports 27 101101 - 101101 2021.9
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Genetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice.
Frederick Adams Ekuban, Cai Zong, Madoka Takikawa, Kota Morikawa, Toshihiro Sakurai, Sahoko Ichihara, Ken Itoh, Masayuki Yamamoto, Seiichiroh Ohsako, Gaku Ichihara
Toxicology 456 152785 - 152785 2021.5
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Health improvement framework for actionable treatment planning using a surrogate Bayesian model
Nakamura Kazuki, Kojima Ryosuke, Uchino Eiichiro, Ono Koh, Yanagita Motoko, Murashita Koichi, Itoh Ken, Nakaji Shigeyuki, Okuno Yasushi
Nature Communications 12 ( 1 ) 3088 - 3088 2021.5
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Capillary Electrophoresis Mass Spectrometry-Based Metabolomics of Plasma Samples from Healthy Subjects in a Cross-Sectional Japanese Population Study.
Hiroyuki Yamamoto, Makoto Suzuki, Rira Matsuta, Kazunori Sasaki, Moon-Il Kang, Kenjiro Kami, Yota Tatara, Ken Itoh, Shigeyuki Nakaji
Metabolites 11 ( 5 ) 314 - 314 2021.5
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Characterization of mitochondrial calpain-5
Yusaku Chukai, Takeshi Iwamoto, Ken Itoh, Hiroshi Tomita, Taku Ozaki
Biochimica et Biophysica Acta - Molecular Cell Research 1868 ( 5 ) 118989 - 118989 2021.4
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Association between Serum Concentration of Carotenoid and Visceral Fat.
Mai Matsumoto, Hiroyuki Suganuma, Naoki Ozato, Sunao Shimizu, Mitsuhiro Katashima, Yoshihisa Katsuragi, Tatsuya Mikami, Ken Itoh, Shigeyuki Nakaji
Nutrients 13 ( 3 ) 912 2021.3
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The CD36 Ligand-Promoted Autophagy Protects Retinal Pigment Epithelial Cells from Oxidative Stress
Marie-France Dorion, Mukandila Mulumba, Shuya Kasai, Ken Itoh, William D. Lubell, Huy Ong
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY 2021 6691402 - 6691402 2021.3
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Pulmonary effects of Fe3O4-PEG-PLGA nanoparticles in wild type and Nrf2 knockout mice following pharyngeal aspiration
SATO Harue, ZONG Cai, DEVINEAU Stéphanie, MCCORD Claire, ICHIHARA Sahoko, BROOKES Oliver, EKUBAN Frederick Adams, ITOH Ken, YAMAMOTO Masayuki, BOLAND Sonja, BAEZA-SQUIBAN Armelle, ICHIHARA Gaku
Annual Meeting of the Japanese Society of Toxicology 48.1 ( 0 ) P-32S 2021
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JDP2 is directly regulated by ATF4 and modulates TRAIL sensitivity by suppressing the ATF4-DR5 axis.
Máté János Engler, Junsei Mimura, Shun Yamazaki, Ken Itoh
FEBS open bio 10 ( 12 ) 2771 - 2779 2020.12
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特集 慢性腎臓病・透析患者の酸化ストレス-最新知見と治療展開 2.慢性腎臓病における酸化ストレス進展機序(1) 慢性腎臓病におけるNrf2-Keap1 経路の役割-CKD 治療薬としての期待
伊東 健, Liu Jun, 葛西 秋宅
臨床透析 36 ( 12 ) 1521 - 1527 2020.11
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Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan
Yasunori Maeda, Akira Sasaki, Shuya Kasai, Shinichi Goto, Shin-ya Nishio, Kaori Sawada, Itoyo Tokuda, Ken Itoh, Shin-ichi Usami, Atsushi Matsubara
HUMAN GENOME VARIATION 7 ( 1 ) 27 - 27 2020.9
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Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging.
Sunao Shimizu, Junsei Mimura, Takanori Hasegawa, Eigo Shimizu, Seiya Imoto, Michiko Tsushima, Shuya Kasai, Hiromi Yamazaki, Yusuke Ushida, Hiroyuki Suganuma, Hirofumi Tomita, Masayuki Yamamoto, Shigeyuki Nakaji, Ken Itoh
PloS one 15 ( 8 ) e0236834 - e0236834 2020.8
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Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness
Mai Matsumoto, Naoko Waki, Hiroyuki Suganuma, Ippei Takahashi, Sizuka Kurauchi, Kahori Sawada, Itoyo Tokuda, Mina Misawa, Masataka Ando, Ken Itoh, Kazushige Ihara, Shigeyuki Nakaji
Nutrients 12 ( 8 ) e2310 - e2310 2020.7
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Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice.
Yoshikazu Yokono, Kenji Hanada, Masato Narita, Yota Tatara, Yousuke Kawamura, Naotake Miura, Kazutaka Kitayama, Masamichi Nakata, Masashi Nozaka, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Ken Itoh, Hirofumi Tomita
Journal of the American Heart Association 9 ( 12 ) e015616 - e015616 2020.6
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Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh
PLoS genetics 16 ( 4 ) e1008693 - e1008693 2020.4