Papers - ITOH KEN
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Transcription factor Nrf2 mediates an adaptilve response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents(共著)
Higgins LG他
Toxicology and applied pharmacology 237 ( 3 ) 267 - 280 2009.6
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Nrf2 enhances cell proliferation and resistance to anticancer drugs in human lung cancer(共著)
Homma S他
Clinical cancer research 15 ( 10 ) 3423 - 3432 2009.5
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Keap1/Nrf2 system regulates neuronal survival as revealed through study of keap1 gene-knockout mice(共著)
Satoh T et al.
Biochemical and Biophysical Research Communications 380 ( 2 ) 298 - 302 2009.3
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Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice(共著)
Prince M. et al.
Toxicological Letter 185 ( 3 ) 180 - 186 2009.3
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Hyperglycemia induces oxidative and nitrosative stress and increases renal functional impairment in Nrf2-deficient mice (共著)
Yoh K. et al.
Genes to Cells 13 ( 11 ) 1159 - 1170 2008.11
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Nrf2 regulates the alternative first exons of CD36 in macrophages through specific antioxidant response elements(共著)
Maruyama A. et al.
Archive of Biochemistry and Biophysics 477 ( 1 ) 139 - 145 2008.9
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Differential roles for Nrf2 and AP-1 in upregulation of HO-1 expression by arsenite in murine embryonic fibroblasts(共著)
Harada H. et al.
Free Radical Research 2 ( 4 ) 297 - 304 2008.7
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Keap1 Regulates the Constitutive Expression of GST A1 during Differentiation of Caco-2 Cells(共著)
Kusano Y
Biochemistry 47 ( 23 ) 6169 - 6177 2008.6
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A Possible Role of Nrf2 in Prevention of Renal Oxidative Damage by Ferric Nitrilotriacetate(共著)
Kanki K. et al.
Toxicological Pathology 36 ( 2 ) 353 - 361 2008.4
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Carnosic acid protects neuronal HT22 Cells through activation of the antioxidant-responsive element in free carboxylic acid- and catechol hydroxyl moieties-dependent manners(共著)
Satoh T et al.
Neuroscience letter 434 ( 3 ) 260 - 265 2008.4
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Induction of cancer chemopreventive enzymes by coffee is mediated by transcription factor Nrf2. Evidence that the coffee-specific diterpenes cafestol and kahweol confer protection against acrolein
Higgins LG et al
Toxicology and applied pharmacology 226 ( 3 ) 328 - 327 2008.2
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Carnosic acid, a catechol-type electrophilic compound, protects neuron both in vitro and in vivo through activation of the Keap1/Nrf2 pathway via S-alkylation of target cysteines on Keap1
Satoh T et al.
Journal of neurochemistry 104 ( 4 ) 1116 - 1131 2008.2
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Attenuation of UVB-Induced Sunburn Reaction and Oxidative DNA Damage with no Alterations in UVB-Induced Skin Carcinogenesis in Nrf2 Gene-Deficient Mice(共著)
Kawachi Y. et al.
Journal of Investigative Dermatology 128 1773 - 1779 2008.1
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Molecular basis distinguishing the DNA binding profile of Nrf2-Maf heterodimer
Kimura M et al.
Journal of biological chemistry 282 ( 46 ) 33681 - 33690 2007.11
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Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carconogenesis
Iida K et al
Carcinogenesis 28 ( 11 ) 2398 - 2403 2007.11
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Subcellular localization and cytoplasmic complex status of endogenous Keap1
Watai Y et al
Gene to Cells 12 ( 10 ) 1163 - 1178 2007.10
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Double-stranded RNA induces galectin-9 in vascular endothelial cells:involvement of TLR3, PI3K, and IRF3 pathway
Imaizumi T et al
Glycobiology 17 ( 7 ) 12C - 15C 2007.7
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Nrf2 Neh5 domain is differentially utilized in the transactivation of cytoprotective genes
Zhang J et al
Biochemical Journal 404 ( 3 ) 459 - 466 2007.6
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Enhanced spontaneous and benzo(a)pyrene-induced mutatins in the lungs of Nrf2-deficient gpt delta mice
Aoki Y et al
Cancer Res 67 ( 12 ) 5643 - 5648 2007.6