Papers - ITOH KEN
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Prevalence of the mitochondrial 1555 A>G and 1494 C>T mutations in a community-dwelling population in Japan
Yasunori Maeda, Akira Sasaki, Shuya Kasai, Shinichi Goto, Shin-ya Nishio, Kaori Sawada, Itoyo Tokuda, Ken Itoh, Shin-ichi Usami, Atsushi Matsubara
HUMAN GENOME VARIATION 7 ( 1 ) 27 - 27 2020.9
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Association of single nucleotide polymorphisms in the NRF2 promoter with vascular stiffness with aging.
Sunao Shimizu, Junsei Mimura, Takanori Hasegawa, Eigo Shimizu, Seiya Imoto, Michiko Tsushima, Shuya Kasai, Hiromi Yamazaki, Yusuke Ushida, Hiroyuki Suganuma, Hirofumi Tomita, Masayuki Yamamoto, Shigeyuki Nakaji, Ken Itoh
PloS one 15 ( 8 ) e0236834 - e0236834 2020.8
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Association between Biomarkers of Cardiovascular Diseases and the Blood Concentration of Carotenoids among the General Population without Apparent Illness
Mai Matsumoto, Naoko Waki, Hiroyuki Suganuma, Ippei Takahashi, Sizuka Kurauchi, Kahori Sawada, Itoyo Tokuda, Mina Misawa, Masataka Ando, Ken Itoh, Kazushige Ihara, Shigeyuki Nakaji
Nutrients 12 ( 8 ) e2310 - e2310 2020.7
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Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice.
Yoshikazu Yokono, Kenji Hanada, Masato Narita, Yota Tatara, Yousuke Kawamura, Naotake Miura, Kazutaka Kitayama, Masamichi Nakata, Masashi Nozaka, Tomo Kato, Natsumi Kudo, Michiko Tsushima, Yuichi Toyama, Ken Itoh, Hirofumi Tomita
Journal of the American Heart Association 9 ( 12 ) e015616 - e015616 2020.6
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Ribosome binding protein GCN1 regulates the cell cycle and cell proliferation and is essential for the embryonic development of mice.
Hiromi Yamazaki, Shuya Kasai, Junsei Mimura, Peng Ye, Atsushi Inose-Maruyama, Kunikazu Tanji, Koichi Wakabayashi, Seiya Mizuno, Fumihiro Sugiyama, Satoru Takahashi, Tsubasa Sato, Taku Ozaki, Douglas R Cavener, Masayuki Yamamoto, Ken Itoh
PLoS genetics 16 ( 4 ) e1008693 - e1008693 2020.4
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Emerging evidence for crosstalk between Nrf2 and mitochondria in physiological homeostasis and in heart disease
Michiko Tsushima, Jun Liu, Wataru Hirao, Hiromi Yamazaki, Hirofumi Tomita, Ken Itoh
Archives of Pharmacal Research 43 ( 3 ) 286 - 296 2020.3
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Deletion of Nrf2 enhances susceptibility to neurotoxic effects of acrylamide in mice
EKUBAN Frederick Adams, ZONG Cai, TAKIKAWA Madoka, MORIKAWA Kouta, SAKURAI Toshihiro, ICHIHARA Sahoko, ITOH Ken, YAMAMOTO Masayuki, OHSAKO Seiichiroh, ICHIHARA Gaku
Annual Meeting of the Japanese Society of Toxicology 47.1 ( 0 ) P-28E 2020
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Nrf2 in the Regulation of Endothelial Cell Homeostasis During Inflammation
Yamazaki, H., Itoh, K.
Progress in Inflammation Research 85 2020
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Health improvement framework for planning actionable treatment process using surrogate Bayesian model.
Kazuki Nakamura, Ryosuke Kojima, Eiichiro Uchino, Koichi Murashita, Ken Itoh, Shigeyuki Nakaji, Yasushi Okuno
CoRR abs/2010.16087 2020
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Role of Nrf2 in inflammatory response in lung of mice exposed to zinc oxide nanoparticles
Radwa Sehsah, Wenting Wu, Sahoko Ichihara, Naozumi Hashimoto, Yoshinori Hasegawa, Cai Zong, Ken Itoh, Masayuki Yamamoto, Ahmed Ali Elsayed, Soheir El-Bestar, Emily Kamel, Gaku Ichihara
Particle and Fibre Toxicology 16 ( 1 ) 47 - 47 2019.12
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定量的プロテオミクス解析による急性期放射線骨髄障害の重症化リスク因子の探索
多田羅 洋太, 門前 暁, 伊東 健
日本生化学会大会プログラム・講演要旨集 92回 [3P - 307] 2019.9
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Concomitant Nrf2- and ATF4-activation by Carnosic Acid Cooperatively Induces Expression of Cytoprotective Genes.
Junsei Mimura, Atsushi Inose-Maruyama, Shusuke Taniuchi, Kunio Kosaka, Hidemi Yoshida, Hiromi Yamazaki, Shuya Kasai, Nobuhiko Harada, Randal J Kaufman, Seiichi Oyadomari, Ken Itoh
International journal of molecular sciences 20 ( 7 ) 1706 2019.4
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Increase of Tumor Infiltrating γδ T-cells in Pancreatic Ductal Adenocarcinoma Through Remodeling of the Extracellular Matrix by a Hyaluronan Synthesis Suppressor, 4-Methylumbelliferone.
Akiko Suto, Daisuke Kudo, Eri Yoshida, Hayato Nagase, Shinichiro Suto, Junsei Mimura, Ken Itoh, Kenichi Hakamada
Pancreas 48 ( 2 ) 292 - 298 2019.2
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Role of the ISR-ATF4 pathway and its cross talk with Nrf2 in mitochondrial quality control
Kasai Shuya, Yamazaki Hiromi, Tanji Kunikazu, Engler Máté János, Matsumiya Tomoh, Itoh Ken
Journal of Clinical Biochemistry and Nutrition 64 ( 1 ) 1 - 12 2019.1
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Aging and APOE-e4 are determinative factors of plasma Ab42 levels.
Takumi Nakamura, Takeshi Kawarabayashi, Yusuke Seino, Mie Hirohata, Naoko Nakahata, Sakiko Narita, Ken Itoh, Shigeyuki Nakaji, Mikio Shoji
Annals of clinical and translational neurology 5 ( 10 ) 1184 - 1191 2018.10
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C151 in KEAP1 is the main cysteine sensor for the cyanoenone class of NRF2 activators, irrespective of molecular size or shape.
Sharadha Dayalan Naidu, Aki Muramatsu, Ryota Saito, Soichiro Asami, Tadashi Honda, Tomonori Hosoya, Ken Itoh, Masayuki Yamamoto, Takafumi Suzuki, Albena T Dinkova-Kostova
Scientific reports 8 ( 1 ) 8037 - 8037 2018.5
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Emerging Regulatory Role of Nrf2 in Iron, Heme, and Hemoglobin Metabolism in Physiology and Disease.
Shuya Kasai, Junsei Mimura, Taku Ozaki, Ken Itoh
Frontiers in veterinary science 5 242 - 242 2018
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Novel roles of glycosaminoglycans in the degradation of type I collagen by cathepsin K.
Yota Tatara, Shinichiro Suto, Ken Itoh
Glycobiology 27 ( 12 ) 1089 - 1098 2017.12
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Increase in proapoptotic activity of inhibitory PAS domain protein via phosphorylation by MK2.
Shuya Kasai, Mary J E Richardson, Satoru Torii, Ken-Ichi Yasumoto, Hiroki Shima, Kazuhiko Igarashi, Ken Itoh, Kazuhiro Sogawa, Kazutaka Murayama
The FEBS journal 284 ( 23 ) 4115 - 4127 2017.12
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Effects of deficiency of Kelch-like ECH-associated protein 1 on skeletal organization: a mechanism for diminished nuclear factor of activated T cells cytoplasmic 1 during osteoclastogenesis.
Eiko Sakai, Masanobu Morita, Masahiro Ohuchi, Mizuho A Kido, Yutaka Fukuma, Kazuhisa Nishishita, Kuniaki Okamoto, Ken Itoh, Masayuki Yamamoto, Takayuki Tsukuba
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 31 ( 9 ) 4011 - 4022 2017.9